Results 61 to 70 of about 146,353 (358)

p38 Mitogen-activated Protein Kinase Regulates Oscillation of Chick Pineal Circadian Clock [PDF]

, 2003
Extracellular signal-regulated kinase (ERK) and p38 are members of the mitogen-activated protein kinase (MAPK) family, and in some cases these kinases serve for closely related cellular functions within a cell. In a wide range of animal clock structures,
Fukada, Yoshitaka, Hayashi, Yuichiro, Hirota, Tsuyoshi, Sanada, Kamon, Shimizu, Fumiko   +4 more
core   +1 more source

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

Differential expression of HIV target cells CCR5 and α4β7 in tissue resident memory CD4 T cells in endocervix during the menstrual cycle of HIV seronegative women

Frontiers in Immunology
BackgroundOvarian hormones are known to modulate the immune system in the female genital tract (FGT). We sought to define the impact of the menstrual cycle on the mucosal HIV target cell levels, and tissue-resident CD4 T cells.Materials and methodsHere ...
Sakthivel Govindaraj, Sakthivel Govindaraj, Staple Tyree, Gina Bailey Herring, Gina Bailey Herring, Sadia J. Rahman, Sadia J. Rahman, Hemalatha Babu, Hemalatha Babu, Chris Ibegbu, Marisa R. Young, C. Christina Mehta, Lisa B. Haddad, Lisa B. Haddad, Alicia K. Smith, Vijayakumar Velu, Vijayakumar Velu   +16 more
doaj   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Double or dual stimulation in poor ovarian responders: where do we stand?

Therapeutic Advances in Reproductive Health, 2021
Recent advances in our recognition of two to three follicular waves of development in a single menstrual cycle has challenged the dogmatic approach of ovarian stimulation for in vitro fertilization starting in the early follicular phase.
Mehtap Polat, Sezcan Mumusoglu, Irem Yarali Ozbek, Gurkan Bozdag, Hakan Yarali   +4 more
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Taking Context to Heart: Momentary Emotions, Menstrual Cycle, and Cardiac Autonomic Regulation [PDF]

, 2019
Background. Emotions have long been discussed in conjunction with the autonomic nervous system. Most research on heart-mood linkages does not consider sex differences or an evident underlying mechanism for sex differences- sex hormone levels.
Simon, Shauna
core  

Follicular and endocrine dose responses according to anti-Müllerian hormone levels in IVF patients treated with a novel human recombinant FSH (FE 999049) [PDF]

, 2015
Objective: To study the association between serum anti-Mullerian hormone (AMH) levels and follicular development and endocrine responses induced by increasing doses (5.2-12.1 mu g/day) of a novel recombinant human FSH (rhFSH, FE 999049) in patients ...
Andersen, Anders Nyboe, Arce, Joan-Carles, Barri, Pedro, Bosch, Ernesto, De Sutter, Petra, Fernández-Sánchez, Manuel, García-Velasco, Juan Antonio, Klein, Bjarke M, Mannaerts, Bernadette, Visnova, Hana   +9 more
core   +2 more sources

The prognostic value of the cytological composition of the tear in the diagnosis of endometriosis

Российский офтальмологический журнал, 2022
Purpose. To investigate the cell composition of the tear in healthy women and endometriosis patients in order to find the potential diagnostic criteria of endometriosis. Material and methods. Tear samples obtained from the lower fornix of the conjunctiva
Y. A. Huseva, O. L. Zharikova, A. V. Vasilevskaya   +2 more
doaj   +1 more source

Follicular-phase endometrial scratching: a truncated randomized controlled trial

Human Reproduction, 2020
Abstract STUDY QUESTION Does intentional endometrial injury (scratching) during the follicular phase of ovarian stimulation (OS) increase the clinical pregnancy rate (CPR) in ART? SUMMARY ANSWER CPR did not vary between the ...
S Santos-Ribeiro, C Blockeel, D Stoop, H Tournaye, P Drakopoulos, H Van de Velde, A Racca, S Mackens   +7 more
openaire   +3 more sources