Results 71 to 80 of about 6,037,422 (381)

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

The influence of the menstrual cycle on acute and persistent pain after laparoscopic cholecystectomy

open access: yesRevista Brasileira de Anestesiologia
Background and objectives: Fluctuations of female sex hormones during menstrual cycle influence pain perception. Endogenous pain inhibition is impaired in follicular phase of menstrual cycle. We tested the primary hypothesis that the women having surgery
Sinem Sari   +7 more
doaj   +1 more source

The effects of oestrogen and progesterone on lymphocyte and plasma cell population in the oviduct and uterine mucosae during follicular and luteal phases in ewes [PDF]

open access: yes, 2011
Hormonal changes during the oestrous cycle influence the immune cells pattern in ewe's reproductive tract, particularly in the uterus and oviduct. This study was conducted to quantify the number of lymphocytes and plasma cells of the uterus and oviduct ...
Abdul Razak, Intan Shameha   +4 more
core  

Solid Lipid Nanoparticles: A Potential Approach for Dermal Drug Delivery [PDF]

open access: yes, 2014
Solid lipid nanoparticles (SLNs) have attracted increasing attention during recent years. Due to their unique size dependent properties, lipid nanoparticles offer possibilities to develop new therapeutics.
Conway, Barbara R, Kakadia, Pratibha G.
core   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Follicular phase endocrine characteristics during ovarian stimulation and GnRH antagonist cotreatment for IVF: RCT comparing recFSH initiated on cycle day 2 or 5.

open access: yesJournal of Clinical Endocrinology and Metabolism, 2011
CONTEXT Strategies involving mild ovarian stimulation protocols for in vitro fertilization (IVF) might lessen discomfort to the patient and substantially lower complication rates. OBJECTIVE The objective of the study was to compare the follicular-phase
C. Blockeel   +6 more
semanticscholar   +1 more source

Changing therapeutic landscape - The last decade [PDF]

open access: yes, 2011
Undoubtedly the most important event in the previous decade in lymphoma treatment was the establishment of immunotherapy as a prime modality. Addition of rituximab improves survival in almost every group of patients with CD20+ tumors. This has led to the
Aurer, Igor
core   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Analysis of Expression Profiles of CircRNA and MiRNA in Oviduct during the Follicular and Luteal Phases of Sheep with Two Fecundity (FecB Gene) Genotypes

open access: yesAnimals, 2021
CircRNA and miRNA, as classes of non-coding RNA, have been found to play pivotal roles in sheep reproduction. There are many reports of circRNA and miRNA in the ovary and uterus, but few in the oviduct. In this study, RNA-Seq was performed to analyze the
Zhifeng Li   +6 more
doaj   +1 more source

Brain responses to food images during the early and late follicular phase of the menstrual cycle in healthy young women: relation to fasting and feeding.

open access: yesAmerican Journal of Clinical Nutrition, 2011
BACKGROUND Food intake fluctuates throughout the menstrual cycle; it is greater during the early follicular and luteal phases than in the late follicular (periovulatory) phase.
M. Alonso-Alonso   +10 more
semanticscholar   +1 more source

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