Italian Journal of Medicine, 2013 AIM OF THE STUDY To review the best evidence-based knowledge about the clinical pharmacology and use of fondaparinux. DESIGN OF THE STUDY Narrative review. RESULTS Fondaparinux is a synthetic pentasaccharide anticoagulant that binds selectively with high
G. Airoldi, M. Campanini
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Associação entre o Uso de Fondaparinux com Acesso Radial e Desfechos Clínicos em Pacientes com Síndrome Coronariana Aguda sem Supradesnivelamento do Segmento ST [PDF]
Arquivos Brasileiros de CardiologiaResumo Fundamento: Tanto o fondaparinux quanto o acesso radial têm sido associados a menores taxas de eventos adversos cardiovasculares maiores (MACE) em pacientes com síndrome coronariana aguda (SCA).
Luiz Eduardo Fonteles Ritt +10 more
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Evaluating the impact of continuous venovenous hemodiafiltration on the efficacy of prophylactic fondaparinux doses: a prospective single-center observational study [PDF]
Scientific ReportsCritically ill patients often need continuous renal replacement therapy (CRRT). This process can remove particles as large as 10 kDa, including medications such as fondaparinux.
Aleksander Aszkiełowicz +2 more
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Efficacy and safety of fondaparinux in elective total hip arthroplasty and hip fracture surgery: a systematic review and meta-analysis [PDF]
Journal of Orthopaedic Surgery and ResearchBackground As life expectancy increases, the incidence of hip fractures and the demand for total hip arthroplasties (THA) are expected to rise. This demographic shift poses significant challenges, particularly in managing post-operative complications ...
Gonzalo Mariscal +6 more
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Maculopathy after long-term use of fondaparinux, a heparin mimetic and heparanase inhibitor [PDF]
American Journal of Ophthalmology Case ReportsPurpose: To report maculopathy associated with the long-term use of fondaparinux, a heparin mimetic and inhibitor of the extracellular matrix enzyme, heparanase.
Benjamin R. Lin +5 more
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Frontiers in Medicine, 2023 Heparin-induced thrombocytopenia is a life-threatening immune-mediated complication of unfractionated heparin therapy. Fondaparinux is a therapeutic alternative, but it has limited evidence for its use in patients on extracorporeal membrane oxygenation ...
Jitka Rychlíčková +6 more
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Fondaparinux monitoring in a patient with heparin-induced thrombocytopenia on hemodialysis [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2016 Introduction. Heparin-induced thrombocytopenia associated to hemodialysis is rare. In case when citrate dialysis and/or non-heparin anticoagulants are not available, only possible medication to use for anticoagulation during hemodialysis is ...
Kušić Jovana +6 more
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IR action spectroscopy of glycosaminoglycan oligosaccharides [PDF]
, 2020 Glycosaminoglycans (GAGs) are a physio- and pharmacologically highly relevant class of complex saccharides, possessing a linear sequence and strongly acidic character.
Freyse, Joanna +9 more
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Frontiers in Cardiovascular Medicine, 2023 BackgroundThis study aims to evaluate the effectiveness and safety of low-dose (1.5 mg) fondaparinux for venous thromboembolism (VTE) prophylaxis in patients post-total knee arthroplasty (TKA).MethodsWe retrospectively identified 314 patients who carried
Ping-bo Chen +8 more
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Fondaparinux Sodium: Recent Advances in the Management of Thrombosis
Journal of Cardiovascular Pharmacology and Therapeutics, 2023 Fondaparinux sodium is a chemically synthesized selective factor Xa inhibitor approved for the prevention and treatment of venous thromboembolic events, that is, deep vein thrombosis, pulmonary embolism, and superficial vein thrombosis, in acutely ill ...
Rupert M. Bauersachs MD
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