Results 21 to 30 of about 32,586 (241)

Failure of Fondaparinux in Autoimmune Heparin-Induced Thrombocytopenia

TH Open, 2020
Heparin-induced thrombocytopenia (HIT) is an immune adverse reaction to heparin that is associated with life-threatening thrombotic complications.
Michelangelo Sartori, Benilde Cosmi
doaj   +2 more sources

Fondaparinux Sodium Compared With Low‐Molecular‐Weight Heparins for Perioperative Surgical Thromboprophylaxis: A Systematic Review and Meta‐analysis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Fondaparinux sodium has been compared with low‐molecular‐weight heparins (LMWH) in randomized controlled trials for perioperative surgical thromboprophylaxis.
Arun Kumar, Ashna Talwar, Joel F. Farley, Jagannath Muzumdar, Jon C. Schommer, Rajesh Balkrishnan, Wenchen Wu   +6 more
doaj   +2 more sources

Antithrombotic and Anti-Inflammatory Effects of Fondaparinux and Enoxaparin in Hospitalized COVID-19 Patients: The FONDENOXAVID Study

Journal of Blood Medicine, 2021
Giuseppe Cardillo,1 Giuseppe Vito Viggiano,2 Vincenzo Russo,3 Sara Mangiacapra,4 Antonella Cavalli,5 Giampiero Castaldo,2 Federica Agrusta,2 Annamaria Bellizzi Snr,5 Maria Amitrano Snr,4 Mariateresa Iannuzzo,6 Clara Sacco,7 Corrado Lodigiani,7 Andrea ...
Cardillo G, Viggiano GV, Russo V, Mangiacapra S, Cavalli A, Castaldo G, Agrusta F, Bellizzi Snr A, Amitrano Snr M, Iannuzzo M, Sacco C, Lodigiani C, Fontanella A, Di Micco P   +13 more
doaj   +2 more sources

Advances in Chemical Synthesis of Fondaparinux

Journal of Chemistry, 2019
Fondaparinux (trade name Arixtra) is a safe and efficacious anticoagulant, and it is chemically related to low-molecular-weight heparins such as enoxaparin. Fondaparinux is a synthetic pentasaccharide, and its synthesis is difficult and expensive.
Yili Ding, Chamakura V. N. S. Vara Prasad, Bingyun Wang   +2 more
doaj   +2 more sources

Antiphospholipid Syndrome Mimicking Acute Exacerbation of Interstitial Pneumonia: A Case Report and Literature Review. [PDF]

Respirol Case Rep
Acute exacerbation of interstitial pneumonia (IP‐AE) is a type of severe respiratory failure that occurs in patients with chronic interstitial pneumonia. However, a few cases of lung involvement caused by antiphospholipid antibody syndrome (APS) appearing similar to IP‐AE have been reported.
Ishii S, Wakabayashi H, Isobe K, Ohashi R, Namba K, Iwayanagi M, Sakurai H, Sakai D, Takashima K, Murakami Y, Kaneko K, Matsuzawa Y.   +11 more
europepmc   +2 more sources

Design and Synthesis of Neutralizable Fondaparinux

JACS Au, 2022
Fondaparinux, a clinically approved anticoagulant pentasaccharide for the treatment of thrombotic diseases, displays better efficacy and biosafety than other heparin-based anticoagulant drugs.
L. Zhang, Yating Liu, Zhuojia Xu, Tianhui Hao, Peng George Wang, Wei Zhao, Tiehai Li   +6 more
semanticscholar   +1 more source

When Will Fondaparinux Induce Thrombocytopenia?

Bioconjugate chemistry, 2022
The pentasaccharide Fondaparinux, a synthetic selective factor Xa inhibitor, is one of the safest anticoagulants in the heparin family that is recommended as an alternative drug for patients with hypersensitivity to other drugs such as heparin-induced ...
Li-Yu Chen, N. Khan, Annerose Lindenbauer, Thi‐Huong Nguyen   +3 more
semanticscholar   +1 more source

Fondaparinux: A cornerstone drug in acute coronary syndromes

World Journal of Cardiology, 2022
In acute coronary syndrome (ACS), the use of anticoagulants in conjunction with antiplatelet agents in the acute phase has resulted in reduced ischemic events and is more effective than either class of drug used alone.
M. Y. Khan, C. Ponde, Vivek Kumar, K. Gaurav   +3 more
semanticscholar   +1 more source

Safety and effectiveness of fondaparinux as a postpartum thromboprophylaxis during puerperium among muslim women: A single centre prospective study

Frontiers in Pharmacology, 2022
Background: Venous thromboembolism (VTE) remains one of the leading causes of maternal morbidity and mortality, with postpartum period carrying the greatest risk. Perinatal thromboprophylaxis is often administered based on risk-factor assessment.
N. Muhamad, M. Abu, A. Kalok, M. Shafiee, S. Shah, Nor Azlin Mohamed Ismail   +5 more
semanticscholar   +1 more source

Promising Drug Fondaparinux for the Treatment of COVID-19: an In Silico Analysis of Low Molecular Weight Heparin, Direct Oral Anticoagulant, and Antiplatelet Drug Interactions with Host Protease Furin

Cardiovascular Drugs and Therapy, 2022
As of July 2022, the COVID-19 pandemic has affected over 555 million worldwide confirmed cases and caused more than 6.3 million deaths. The studies showed that the D-dimer levels were increased in non-survivors compared to survivors and heparin treatment
T. Ertan-Bolelli, Kayhan Bolelli, Sıtkı Doga Elçi, F. B. Belen-Apak   +3 more
semanticscholar   +1 more source