Detection of Genetically Modified Food: Has Your Food Been Genetically Modified?
openaire +2 more sources
PANEs are specifically designed to enhance the brain delivery efficiency of circDYM compared to commercialized lipid nanoparticles (LNPs). Intranasal administration of PANE‐circDYM effectively alleviated LPS‐induced depressive‐like behaviors by mitigating neuroinflammation and promoting neuroplasticity.
Feng Gao+11 more
wiley +1 more source
Safety evaluation of an extension of use of the food enzyme endo-1,4-β-xylanase from the genetically modified <i>Aspergillus niger</i> strain XEA. [PDF]
EFSA Panel on Food Enzymes (FEZ)+16 more
europepmc +1 more source
Isoquercitrin Alleviates Diabetic Nephropathy by Inhibiting STAT3 Phosphorylation and Dimerization
This study identified a natural compound, isoquercitrin, which significantly alleviated kidney inflammation and fibrosis by inhibiting STAT3 activity. Isoquercitrin forms a strong, noncovalent bond that directly binds to STAT3. Isoquercitrin binds to the pY+1 pocket of the SH2 domain of STAT3 via hydrogen bonding with Ser668, Gln635, and Gln633 ...
Chen Xuan+12 more
wiley +1 more source
Assessment of genetically modified sugar beet KWS20-1 (application GMFF-2023-14732). [PDF]
EFSA Panel on Genetically Modified Organisms (GMO)+30 more
europepmc +1 more source
MYC is a transcription factor (TF) that binds DNA near transcriptional start sites (TSSs) and within enhancer elements. Here, unappreciated sites of MYC binding in the vicinity of transcriptional end sites (TESs) of many genes in multiple cell types in association with numerous other TFs are described previously.
Huabo Wang+5 more
wiley +1 more source
Safety evaluation of the food enzyme β-fructofuranosidase from the genetically modified <i>Trichoderma reesei</i> strain AR-996. [PDF]
EFSA Panel on Food Enzymes (FEZ)+21 more
europepmc +1 more source
Detecting Genetically Modified Products in Food. [PDF]
openaire +3 more sources
This study defines the structure, mechanics, and mechanobiology of the fibrocartilage pericellular matrix (PCM) using the murine meniscus, showing how collagen V deficiency alters PCM properties and disrupts cell mechanosensitive signaling. Findings emphasize the critical role of PCM in fibrocartilage mechanobiology and suggest targeting it can enhance
Chao Wang+13 more
wiley +1 more source
Updated safety evaluation of the food enzyme endo-1,4-β-xylanase from the genetically modified <i>Aspergillus niger</i> strain XYL. [PDF]
EFSA Panel on Food Enzymes (FEZ)+19 more
europepmc +1 more source