Results 81 to 90 of about 1,215,657 (309)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Rice bran oil rescues cognitive decline in D-galactose-induced aging mice by inhibiting Aβ accumulation and Tau hyperphosphorylation induced oxidative stress and neuroinflammation

open access: yesFood Science and Human Wellness
Alzheimer's disease (AD) is a neurodegenerative disorder associated with brain aging, and the accumulation of β-amyloid (Aβ) and hyperphosphorylated Tau proteins are key pathological features.
Yadan Zhang   +5 more
doaj   +1 more source

Determination of Illegally Added Digitalis Drugs in Health Foods by Ultra-high Performance Liquid Chromatography-Tandem Mass Spectrometry [PDF]

open access: yesShipin Kexue
A method for the determination of six illegally added digitalis drugs (methyldigoxin, digoxin, deslanoside, digitoxin, strophanthidin, lanatoside C) in health foods was established by ultra-high performance liquid chromatography-tandem mass spectrometry (
PAN Cheng, HUANG Qian, FU Minhao, LIN Bowei, LIAO Xiaolei, LIN Qin
doaj   +1 more source

HORIZONTAL AND VERTICAL INTRA-INDUSTRY TRADE IN THE PROCESSED FOOD SECTOR [PDF]

open access: yes
For the first time in the food trade literature, the determinants of intra-industry trade (IIT) in horizontally differentiated products and vertically differentiated products are separately tested using the most recent theoretical models of IIT. For both
Frahan, Bruno Henry de, Tharakan, Joe
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Enhancing postharvest storage quality and cuticular wax composition of summer black grapes through preharvest calcium application

open access: yesFood Chemistry: X
This study investigated the effects of preharvest calcium treatments at different developmental stages on the cuticular wax composition of Summer Black grapes and their correlation with fruit storage quality (4 ± 0.5 °C) and reactive oxygen species (ROS)
Yaoying Zeng   +9 more
doaj   +1 more source

No. 04: Supermarkets, Wet Markets and Food Patronage in Nanjing, China [PDF]

open access: yes, 2016
Although supermarkets have become a dominant food outlet for urban residents in developed countries, studies of food purchasing in developing countries such as China report a persistence of traditional food outlets, despite a proliferation of ...
McCordic, Cameron   +2 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Ultra-Processed Food Intake and Risk of Type 2 Diabetes Mellitus: A Dose-Response Meta-Analysis of Prospective Studies [PDF]

open access: yesDiabetes & Metabolism Journal
Background Although some studies suggest a positive association between ultra-processed food (UPF) intake and type 2 diabetes mellitus (T2DM), little is known about the exact shape and risks associated with different units (percentage of g/day, absolute ...
Yujin Kim   +4 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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