Results 81 to 90 of about 449,984 (280)

Compliance with national guidelines for the management of drug-drug interactions in Dutch community pharmacies.

, 2007
Item does not contain fulltextBACKGROUND: Pharmacists contribute to the detection and prevention of drug therapy-related problems, including drug-drug interactions.
Schalekamp, T., Dep Farmaceutische wetenschappen, Smet, P.A.G.M. de, Population-based studies of drug treatment: from molecule to patient outcomes, Egberts, A.C.G., de Smet, A.G.M., Buurma, H.   +6 more
core   +1 more source

FOOD/DRUG AND DRUG/NUTRIENT INTERACTIONS: What You Should Know About Your Medications

EDIS, 2009
Revised! FCS-8092, a 10-page fact sheet by Linda Bobroff, Ashley Lentz, and R. Elaine Turner, describes common food/drug and drug/nutrient, and how consumers can see the potential for interactions and learn to avoid them. Includes references.
Linda B. Bobroff, Ashley Lentz, R. Elaine Turner   +2 more
doaj   +5 more sources

ArcDFI: Attention regularization guided by CYP450 interactions for predicting drug-food interactions.

PLoS Computational Biology
CYP450 isoenzymes are known to be deeply involved in the formation of drug-food interactions (DFI). Previously introduced computational approaches for predicting DFIs do not take drug-CYP450 interactions (DCI) into account and have limited ...
Mogan Gim, Jaewoo Kang, Donghyeon Park, Minji Jeon   +3 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Food Additives Inhibit Intestinal Drug Transporters but Have Limited Effect on In Vitro Drug Permeability

Food additives are chemical substances that are added to processed food to improve its flavor, texture, or appearance. Food additives can inhibit intestinal transporters, such as breast cancer resistance protein (BCRP), multidrug resistance associated ...
Stenberg, Emilia, Sjöstedt, Noora Karoliina, Kidron, Heidi Tuulia, Suominen, Laura Maria Vilhelmiina   +3 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Food Bioactive Compounds and Their Interference in Drug Pharmacokinetic/Pharmacodynamic Profiles

Pharmaceutics, 2018
Preclinical and clinical studies suggest that many food molecules could interact with drug transporters and metabolizing enzymes through different mechanisms, which are predictive of what would be observed clinically.
Matteo Briguglio, Silvana Hrelia, Marco Malaguti, Loredana Serpe, Roberto Canaparo, Bernardo Dell’Osso, Roberta Galentino, Sara De Michele, Carlotta Zanaboni Dina, Mauro Porta, Giuseppe Banfi   +10 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Reporting Patterns Indicative of Adverse Drug Interactions

, 2011
Background: Adverse drug interaction surveillance in collections of Individual Case Safety Reports (ICSRs) remains underdeveloped. Most efforts to date have focused on disproportionality analysis, but the empirical support for its value is based on ...
Bate, Andrew,, Caster, Ola,, Andrew Bate, Ola Caster, Bate, Andrew, I. Ralph Edwards, Norén, Niklas,, Niklas Norén, Edwards, I. Ralph, Strandell, Johanna,, Strandell, Johanna, Edwards, I Ralph,, Johanna Strandell   +12 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source