Results 31 to 40 of about 865,259 (266)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Globalization of Slovenian Agricultural and Food Trade [PDF]

open access: yes
This paper analyses globalization patterns in the Slovenian agricultural and food trade. It examines prevailing trade structures and trade types to study differences and similarities in trade specialization patterns between primary and processed ...
Darja Majkovic, Stefan Bojnec
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Trade Types in Slovenian Primary and Processed Agricultural Trade [PDF]

open access: yes
The significance of the processed food products in agricultural and food trade is increasing in Slovenia as well as in the other developed countries. The large share of agricultural and food trade is inter-industry trade.
Bojnec, Stefan   +2 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Technical efficiency in the Chilean agribusiness sector [PDF]

open access: yes
The reform-process towards a higher world-market orientation has a long tradition in Chile, with all its strengths and weaknesses. The food processing industry is highly competitive on the worldmarket.
Brümmer, Bernhard   +2 more
core  

Towards more ecoefficient food production: MFA approach [PDF]

open access: yes, 2004
The food flux comprises four mutually linked loops: 1)plant production, 2)livestock husbandry, 3) food processing industry and 4) human consumption. In the present paper MFA approach has been used to describe the system. A general framework and practical
Koikkalainen, K.   +4 more
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Improvised design of grease trap for the usage at the food premises [PDF]

open access: yes, 2020
In Malaysia, there are many pollutions that emitted from the industry. Water pollution can be caused by various sectors, one of it is the industrial sector of the food service.
Hamidon, Nuramidah   +5 more
core  

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