Results 121 to 130 of about 3,160,663 (305)
59 p.Summarizes the main conclusions reached by experts commissioned to evaluate the safety of selected food additives and contaminants. Available chemical, biological, and toxicological data are used to identify health hazards, establish standards for ...
World Health Organization +2 more
core
Burkholderia gladioli pathovar cocovenenans (BGC) is a highly lethal foodborne pathogen responsible for outbreaks of food poisoning with the highest recorded mortality rates among bacterial foodborne illnesses in China.
Mengmeng Li +3 more
doaj +1 more source
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
v, 279 p.This publication contains monographs prepared at the one-hundredth meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), held in Rome from 10 to 19 June 2025. It presents the Committee’s evaluation of selected food additives,
World Health Organization +1 more
core
Heterocyclic aromatic amines (HAAs), known for their mutagenic and carcinogenic potential, are formed during the heating of protein-rich food items.
Yang Wang +3 more
doaj +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
vii, 293 p.This volume of the WHO Food Additives Series presents the toxicological and dietary exposure evaluations prepared by the ninety-seventh meeting of the Joint FAO/WHO Expert Committee on Food Additives (JECFA), held in Rome in October–November ...
World Health Organization +1 more
core
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Food additives have been categorised as colours, sweeteners and miscellaneous additives. Overall, additives have 27 functions, amongst which preservation of foodstuffs is a major role.
Peter J. Aggett
core +1 more source

