Results 71 to 80 of about 421,892 (254)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Exploring scenario guided pathways for food assistance in Tuscany

open access: yesBio-based and Applied Economics, 2017
A growing number of people in high income countries, also from the segments of population once considered secure, seek food assistance. Diverse food aid initiatives and practices are developed by a range of actors to tackle food poverty; alongside ...
Francesca Galli   +4 more
doaj   +1 more source

The impact of assistance on poverty and food security in a fragile and protracted-crisis context: the case of West Bank and Gaza Strip

open access: yesBio-based and Applied Economics, 2020
This paper assesses the impact of assistance on the wellbeing of Palestinian households. The impact evaluation analysis uses a difference-in-difference approach for the treatment of sample selection bias. The paper uses data from the 2013 and 2014 rounds
Donato Romano   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Food assistance is associated with improved body mass index, food security and attendance at clinic in an HIV program in central Haiti: a prospective observational cohort study

open access: yesAIDS Research and Therapy, 2010
Background Few data are available to guide programmatic solutions to the overlapping problems of undernutrition and HIV infection. We evaluated the impact of food assistance on patient outcomes in a comprehensive HIV program in central Haiti in a ...
Ivers Louise C   +3 more
doaj   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

open access: yesFEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile   +8 more
wiley   +1 more source

Democracia alimentar para populações em vulnerabilidade social: o caso de cozinhas solidárias em Manaus, Amazonas

open access: yesConfins
Following the COVID-19 pandemic, there has been a significant increase in collaboration between various public, private and civil organizations. These initiatives include solidarity kitchens, which are based on the principle of the Human Right to ...
Camila Lago Braga   +1 more
doaj   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

open access: yesFEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

The Folly of Food Waste amidst Food Insecurity in the United States: A Literature Review

open access: yesChallenges
Food insecurity is an economic and social condition that involves individuals having limited or uncertain access to healthy food. Despite the well-intentioned efforts of both governmental and not-for-profit organizations in addressing food insecurity ...
Michael F. Royer
doaj   +1 more source

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