Results 111 to 120 of about 175,924 (305)

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

Advanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach, Jonas Kubat, Stefan Simm, Alexandra H. Springwald, Burak Demir, Anton Liebezeit, Michael C. Hacker, Michaela Schulz‐Siegmund   +7 more
wiley   +1 more source

Start, Stop, Rewind, Repeat—Cyclic Exposure of Adipose Stromal Cells‐derived Cartilage Organoids to Chondrogenic and Proliferative Cues to Achieve Scaled‐up and Customizable Bone Formation by Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
This study exploits the plasticity of ASCs‐derived cartilage organoids which generate a perichondrial layer of MSCs when exposed to cyclic chondrogenic/proliferative cues. Using these organoids as building blocks, we develop (i) Phalange Shaped Tissue Engineered Cartilage (Pa‐TECs), recapitulating endochondral ossification suitable for the treatment of
Pablo Pfister, Emilien Lhospice, Andrés García‐García, Robert Paillaud, Sebastian Jung, Romain Schaller, Elisabeth A. Kappos, Claude Jaquiéry, Tarek Ismail, Dirk J. Schaefer, Michael de Wild, Ivan Martin, Alexandre Kaempfen, Arnaud Scherberich, Adrien Moya   +14 more
wiley   +1 more source

The attractiveness of the urban name: food outlets

Journal of Applied Linguistics and Lexicography, 2019
The article presents a piece of research in the sphere of urban onomastics which is becoming increasingly popular among Russian linguists, and gives a general overview of such studies with references to recent publications. The article discusses an element of the urban onomasticon, specifically, the names of eating establishments (“trapezonyms”) from ...
openaire   +2 more sources

Design and Synthesis of Peptide‐Polyester Conjugates for Cell‐Mediated Scaffold Degradation

Advanced Healthcare Materials, EarlyView.
This work describes polycaprolactone (PCL)‐based biomaterials engineered to degrade in response to cell‐secreted proteases. A fast‐degrading peptide (Fast) sequence is integrated into a PCL conjugate backbone to produce a biomaterial that is selectively degraded by multiple cell types compared to its scrambled control (ScrFast).
Korina Vida G. Sinad, Natasha K. Hunt, Srujan Singh, Kelly B. Seims, Yingjie Wu, E. Thomas Pashuck, Warren L. Grayson, Lesley W. Chow   +7 more
wiley   +1 more source

Exploring tourism attractiveness factors and consumption patterns of Southeast Asian tourists to Taiwan

Cogent Social Sciences
In an attempt to drive tourist interest, Taiwan implemented a series of changes in 2016 seeking to attract new and repeat visitors. Using a sample of 2339 international tourists visiting Taiwan from 2017 to 2020, we aimed to analyze the attractiveness ...
Wei-Tse Pai, Jie-Min Lee, Ji-Feng Ding, Ca-Van Pham   +3 more
doaj   +1 more source

Household Level Financial Incentives to Adoption of Conservation Agricultural Technologies in Africa [PDF]

Although several studies have been conducted to determine the viability of conservation agriculture in Sub-Saharan Africa, almost all such studies are fragmented – often country specific – and with undue emphasis on output effects. However, assessment of
Donovan, Cynthia, Haggblade, Steven, Tembo, Gelson   +2 more
core   +1 more source

Diels‐Alder Click Chemistry as a Dynamic‐Covalent Crosslinking Method in Spheroid‐Encapsulating Hydrogels for Cartilage Engineering

Advanced Healthcare Materials, EarlyView.
This research shows the development of hydrogels with Diels‐Alder click chemistry for engineering cartilage‐like tissue. The hydrogels support cartilage spheroids which could be cultured for at least 28 days. Furthermore, the spheroids showed a tendency to fuse together into a more consistent construct, and produced important components needed for ...
Sanne M. van de Looij, Antonia G. Vasilopoulou, Lennard Spauwen, Antoinette van den Dikkenberg, Jasmijn V. Korpershoek, Mylene de Ruijter, Jos Malda, Bas G. P. van Ravensteijn, Tina Vermonden   +8 more
wiley   +1 more source

Organizational - economic mechanism of increase of competitiveness of domestic food products: a regional perspective

Путеводитель предпринимателя, 2020
The article considers the conditions of increasing of competitiveness of food products in the region, which include: an innovative approach, the availability offactors of production and legal conditions for competition and strategic development, first of
V. E. Gladkova, V. R. Zharikov, E. S. Zhangalieva   +2 more
doaj  

From RNA to DNA: How Cargo Identity Reprograms Lipid Nanoparticle Architecture and Function

Advanced Healthcare Materials, EarlyView.
The evolution of lipid nanoparticles (LNPs) spans from RNA‐LNPs, used in mRNA vaccines, to DNA‐LNPs, ideal for gene therapies. Emerging bionano architectures, decorated with DNA and plasma proteins, pave the way for advanced DNA‐based therapies that are more stable, targeted, and customizable.
Erica Quagliarini, Daniela Pozzi, Giulio Caracciolo   +2 more
wiley   +1 more source

Stakeholder involvement in policy evaluation and development in 11 European countries: synthesis results [PDF]

, 2006
In an effort in bringing together stakeholders of the organic farming and general agricultural policy sector within the EU in April Mai 2004 a group of stakeholders met for a one day-workshop in 11 European countries (AT, GB, DE, DK, IT, CH, CZ, PL, SI ...
Dabbert, S., Häring, A.M, Vairo, D., Zanoli, R.   +3 more
core