Results 51 to 60 of about 300,026 (315)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
EFSA Journal, 2016 Amygdalin is the major cyanogenic glycoside present in apricot kernels and is degraded to cyanide by chewing or grinding. Cyanide is of high acute toxicity in humans. The lethal dose is reported to be 0.5–3.5 mg/kg body weight (bw).
EFSA Panel on Contaminants in the Food Chain (CONTAM)
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
EFSA Journal, 2014 Beauvericin and enniatins are mycotoxins produced by various Fusarium species. The European Commission asked EFSA for a scientific opinion on the risk to human and animal health related to the presence of beauvericin and enniatins in food and feed.
EFSA Panel on Contaminants in the Food Chain (CONTAM)
doaj +1 more source
Bioaccumulation modelling and sensitivity analysis for discovering key players in contaminated food webs: the case study of PCBs in the Adriatic Sea [PDF]
, 2015 Modelling bioaccumulation processes at the food web level is the main step to analyse the effects of pollutants at the global ecosystem level. A crucial question is understanding which species play a key role in the trophic transfer of contaminants to ...
Marianna Taffi a, D +3 more
core +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Global health and economic impacts of mycotoxins: a comprehensive review
Environmental Sciences EuropeMycotoxins pose significant health and economic challenges, affecting humans, animals, and commodities. This review examines fungal toxigenicity, its spread, and its impact on crops, ecosystems, and human health.
Amira A. Goda +13 more
doaj +1 more source
Scientific Opinion on Emerging and Novel Brominated Flame Retardants (BFRs) in Food [PDF]
EFSA Journal, 2012 EFSA was asked to deliver a scientific opinion on brominated flame retardants (BFRs) other than PBDEs, PBBs, HBCDDs, TBBPA and brominated phenols and their derivatives.
EFSA Panel on Contaminants in the Food Chain (CONTAM)
doaj +1 more source
How Cultural Perceptions and Food Preparation Affect Westerners View of Insects as Food [PDF]
, 2018 There has been a recent push to encourage westerners to introduce insects into their diets. Traditional arguments that stress environmental and nutritional benefits have been largely unsuccessful.
Grosdidier, Raymond +2 more
core
FEBS Open Bio, EarlyView.This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc +8 more
wiley +1 more source