Results 61 to 70 of about 4,823,473 (313)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Staphylococcus food poisoning: recommendations for its prevention and control [PDF]

open access: yes, 1967
Mr. Dewberry, a Fellow of the Society of Health and of the Institute of Public Health and Hygiene, served with The historic Mediterranean Fever Commission in Malta in 1904-05 and may be the last survivor of that celebrated group.
Dewberry, Elliot B.
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Regular Expression Based Online Aided Decision Making Knowledge Base for Quality and Security of Food Processing

open access: yesCybernetics and Information Technologies, 2015
With regard to the inefficient application of a food processing information system due to shortage of the knowledge acquisition measure and self-updating function of knowledge, a method of constructing an online aided decision making knowledge base for ...
Wen Liu   +5 more
doaj   +1 more source

The European Union One Health 2022 Zoonoses Report

open access: yesEFSA Journal, 2023
This report by the European Food Safety Authority and the European Centre for Disease Prevention and Control presents the results of the zoonoses monitoring and surveillance activities carried out in 2022 in 27 Member States (MSs), the United Kingdom ...
European Food Safety Authority (EFSA)   +1 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Investigating the Factors Affecting Consumer Purchase Intention towards Halal Organic Food [PDF]

open access: yes, 2019
Organic food industry is currently one of the emerging markets around the world. People begin to realize the advantages of using organic instead of conventional food.
Abdul Wahid, Nabsiah   +2 more
core   +1 more source

Personal determinants of organic food consumption: a review [PDF]

open access: yes, 2009
Purpose - A lot of literature is available that discusses personal determinants of organic food consumption. However different models and determinants are used in the literature. This paper aims to provide an overview, within a framework linking Schwartz'
Aertsens, Joris   +3 more
core   +2 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Quality analysis of critical control points within the whole food chain and their impact on food quality, safety and health (QACCP) [PDF]

open access: yes, 2010
The overall objective of the project was to optimise organic production and processing in order to improve food quality and increase health promoting aspects in consumer products.
Kahl, Johannes   +6 more
core  

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