Results 151 to 160 of about 19,137 (229)

Negative Affective States Are Not Detected in Rats Following an Intravenous Self‐Administration Regimen Leading to Incubation of Oxycodone Craving

open access: yesAddiction Biology, Volume 31, Issue 11, November 2026.
This study asked whether negative affective states are detected in rats after protracted abstinence from an oxycodone self‐administration regimen leading to incubation of craving. After more than 40 days of abstinence, when incubation is robust, we found no differences between saline and oxycodone rats in tests of negative affect.
Amanda M. Wunsch   +7 more
wiley   +1 more source

Controlled breathing and heart rate variability biofeedback for substance use‐related outcomes: A systematic review and meta‐analysis

open access: yesAddiction, Volume 121, Issue 11, Page 2959-2971, November 2026.
Abstract Background and aim Substance use disorders (SUDs) contribute significantly to global social and economic burden. Breathing‐based interventions offer a low‐cost, scalable adjunct or alternative to traditional treatment, yet their effects on substance use‐related outcomes has not been systematically evaluated.
Ariel Dart Roxburgh   +7 more
wiley   +1 more source

Proof‐of‐concept trial of PP‐01 for mitigating cannabis withdrawal syndrome in participants with cannabis use disorder

open access: yesThe American Journal on Addictions, Volume 35, Issue 6, Page 739-747, November 2026.
Abstract Background and Objectives Cannabis withdrawal symptoms can be severe and protracted, significantly impeding the ability to abstain from cannabis use, resulting in failed quit attempts and relapse. This clinical trial evaluated safety and efficacy of PP‐01, a novel dual‑mechanism of action, investigational agent, for mitigating cannabis ...
Ashley F. Slagle   +4 more
wiley   +1 more source

‘It's a Balancing Act’: A Qualitative Analysis of the Experiences of Caffeine Use in Individuals With Bipolar Disorder

open access: yesBipolar Disorders, Volume 28, Issue 7, November 2026.
ABSTRACT Introduction Bipolar Disorder (BD) is a complex and often chronic mood disorder that can cause significant distress and disruption to everyday life. The condition often requires lifelong treatment and self‐management. Caffeine is a lifestyle behaviour that could be useful in self‐management alongside traditional treatments, but further ...
Sammy Eden   +4 more
wiley   +1 more source

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