CAF‐derived exosomes deliver circFAD104 into TNBC cells, where it acts as a molecular scaffold that bridges the E3 ligase MARCHF8 and PGM1, promoting MARCHF8‐mediated K48‐linked ubiquitination and proteasomal degradation of PGM1. Loss of PGM1 redirects glucose‐phosphate flux from glycogen synthesis toward glycolysis, thereby driving stemness, EMT, and ...
Lei Wang +16 more
wiley +1 more source
Democratic governance through DAO-based deliberation and voting for inclusive decision making in AI models. [PDF]
Sharma T +8 more
europepmc +1 more source
Intrinsically stretchable OECTs enable bifunctional operations via gate engineering. Polarizable Ag/AgCl gates provide volatile sensing, while Au gates enable non‐volatile memory. The SEBS‐blended channel maintains performance under strain, supporting reliable signal transduction.
Jiyong Yoon +8 more
wiley +1 more source
Strengthening climate-health literacy through sustainability education among dental students: a quasi-experimental evaluation. [PDF]
Sönmez ÖF +4 more
europepmc +1 more source
AMT‐676 is a novel antibody‐drug conjugate targeting CDH17, an adhesion molecule uniquely exposed on gastrointestinal tumor surfaces. Engineered with an optimized exatecan payload, it demonstrates profound tumor regression and a robust bystander effect across diverse preclinical models.
Ying‐nan Wang +21 more
wiley +1 more source
Promoting Health Equity in an Era of Growing Contradictions Between Capital Accumulation and Social Reproduction in Capitalist Economies. [PDF]
Raphael D, Bryant T, Amin R.
europepmc +1 more source
A thrombin‐functionalized copper‐polydopamine nanofiber sponge integrates rapid hemostasis, mild photothermal antibacterial therapy, stimulus‐responsive Cu2+ release, chemodynamic oxidative stress, and macrophage immunomodulation. This multifunctional dressing suppresses infection, regulates inflammation, promotes angiogenesis and re‐epithelialization,
Ziwei Zhang +11 more
wiley +1 more source
From marginalization to transformation: Examining structural injustices and policy impacts on Albania's Roma and Egyptian communities. [PDF]
Dervishi E.
europepmc +1 more source
A CD14‐Targeting In Situ Hydrogel Directs Macrophage Reprogramming to Minimize Scar Formation
A CD14‐targeting in situ hydrogel formed from a microbial polysaccharide rapidly remodels the immune microenvironment by reprogramming macrophage polarization, suppressing excessive inflammation, and coordinating tissue regeneration. This multifunctional hydrogel promotes scar‐reduced wound repair through enhanced angiogenesis, collagen remodeling, and
Rui Fang +5 more
wiley +1 more source
Climate Change Perceptions Scale for Health and Related Professionals and Students (CCPS-HARPS) - development, reliability and validity. [PDF]
Sönmez ÖF, Başer A, Sofuoğlu Z.
europepmc +1 more source

