Results 41 to 50 of about 11,988 (256)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Desertos alimentares e a sua espacialização na metrópole de Curitiba, Brasil
ConfinsThe article develops the food desert concept under the urban planning perspective and presents three investigations about the spatialization of the food deserts in the metropolis of Curitiba, Brazil.
Marina Sutile de Lima
doaj +1 more source
Using Open Source Data to Identify Transit Deserts in Four Major Chinese Cities
ISPRS International Journal of Geo-Information, 2020 The concept of transit deserts stems from the concept of food deserts. There is substantial research on transit deserts in developed countries. However, there is no known research that has studied this subject in Chinese cities.
Junfeng Jiao, Mingming Cai
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Food Insecurity and Food Deserts [PDF]
, 2021 The Home & Garden Information Center provides research-based information on landscaping, gardening, plant health, household pests, food safety and preservation, nutrition, physical activity, and health.
Clemson University, Cooperative Extension Service
core
È possibile una gestione “ideale” della pandemia da malattia renale cronica?
Giornale di Clinica Nefrologia e Dialisi, 2022 Chronic Kidney Disease (CKD) is recognized as one of the major categories of noncommunicable epidemic diseases and in the last decades it has been largely growing in incidence and prevalence all over the world.
Stefano Michelassi
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Journal of Agriculture, Food Systems, and Community Development, 2016 There is generally consensus regarding the methodology used to identify and visualize food deserts in urban centers, and to a lesser extent those in rural communities.
John Van Hoesen +2 more
doaj +1 more source