Neutrophil‐Mimetic MRI Enables Ultra‐Early Detection of Vascular Inflammation After Stroke
In this study, we developed neutrophil‐mimetic MRI probes that detect ultra‐early neuroinflammation following ischemic stroke by targeting E‐selectin. Within seconds of their injection, these microparticles mimic initial leukocyte adhesion to the activated cerebral endothelium.
Marion Isabelle Morvan +17 more
wiley +1 more source
Safety evaluation of the food enzyme papain, a cysteine endopeptidase complex from the latex of <i>Carica papaya</i> L. [PDF]
EFSA Panel on Food Enzymes (FEZ) +15 more
europepmc +3 more sources
Safety evaluation of the food enzyme β-glucosidase from the genetically modified <i>Trichoderma reesei</i> strain DP-Nyk114. [PDF]
EFSA Panel on Food Enzymes (FEZ) +17 more
europepmc +1 more source
Natural Biomaterials for Osteochondral Repair: From Source to Strategy
Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu +5 more
wiley +1 more source
Revised safety evaluation of the food enzyme catalase from the non-genetically modified <i>Aspergillus niger</i> strain CTS2093. [PDF]
EFSA Panel on Food Enzymes (FEZ) +18 more
europepmc +1 more source
Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine
A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen +5 more
wiley +1 more source
Safety evaluation of the food enzyme phospholipase D from the genetically modified <i>Streptomyces violaceoruber</i> strain pPDN. [PDF]
EFSA Panel on Food Enzymes (FEZ) +20 more
europepmc +1 more source
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Safety evaluation of the food enzyme glutaminase from the genetically modified <i>Bacillus subtilis</i> strain Glu3-3. [PDF]
EFSA Panel on Food Enzymes (FEZ) +16 more
europepmc +1 more source
Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley +1 more source

