Results 131 to 140 of about 47,916 (257)

Exploring the Potential Role of Hydroxytyrosol in Androgenetic Alopecia: An Integrated Bioinformatics and Molecular Simulation Study. [PDF]

Int J Mol Sci
Zhang L, An X, Xu M.
europepmc   +1 more source

From Food Hubs to Cult Sities

AbstractThis paper challenges the traditional "funerary" paradigm of ancient structures such as the Minoan Labyrinths, Egyptian Pyramids (specifically the Djoser complex), and the underground cities of Cappadocia (Derinkuyu). The author proposes a "Logistic-Pragmatic" hypothesis, suggesting that these complexes were originally engineered as high-tech ...
openaire   +1 more source

Targeting a Myeloid–Regulatory B Cell Network Reverses Immune Paralysis in Periprosthetic Joint Infections

Advanced Science, EarlyView.
Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu, Shutao Zhang, Yumin Lin, Juyang Jiao, Zhiwei Fu, Qimin Hong, Ziyi Zhao, Xinhua Qu, Fei Su, Bing Yue   +9 more
wiley   +1 more source

Exploring the potential targets and mechanisms of malachite green induced lung adenocarcinoma through network toxicology and molecular docking. [PDF]

Medicine (Baltimore)
Qu S, Yang Z, Zhang S, Hou Y.
europepmc   +1 more source

Targeting the HSPA8‐CMA‐ATP6V1A Axis Triggers Lysosomal Hyperacidification and Catastrophic Vacuolation in Prostate Cancer

Advanced Science, EarlyView.
Our experimental evidence supports a model in which ALO targets the HSPA8‐CMA‐ATP6V1A axis to induce lysosomal hyperacidification and initiate osmotic and lipidomic stress. These changes are associated with LMP and loss of lysosomal integrity in prostate cancer cells.
Bingzheng An, Ze Gao, Shuo Chen, Liwei Meng, Chen Zhang, Kefan Song, Haochen Cui, Lei Yan, Zhiqing Fang   +8 more
wiley   +1 more source

Unity Food Hub: Creating New Opportunities for Local Farms

Maine Policy Review, 2011
Michael Gold
doaj  

Gi4SaveLife: a community-led model for sustainable voluntary blood donation in rural Sierra Leone. [PDF]

BMJ Glob Health
Fernandez Turienzo C, November L, Turay M, Kamara P, Lassie RK, Kamara JS, Kamara MK, Kamara M, Duraman M, Kuhrt K, Leather AJM, Gevao S, Williams PT.   +12 more
europepmc   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

The Renaissance of a Food-Based Economy in Skowhegan

Maine Policy Review, 2011
Amber Lambke
doaj  

Conserved regulatory modules and hub genes linking leaf transcriptomes to soybean seed weight. [PDF]

BMC Plant Biol
Bruggink J, Wozny J, Golshani A, Cober E, Samanfar B.   +4 more
europepmc   +1 more source