Results 121 to 130 of about 3,536,825 (286)

GSTM4 Suppresses Prostate Cancer Progression by Targeting TRIM27‐mediated ACLY Ubiquitination and Lipid Metabolism

Advanced Science, EarlyView.
GSTM4 enhances the interaction between ACLY and the E3 ubiquitin ligase TRIM27, thereby increasing K48‐linked ubiquitination at the K554 site of ACLY and promoting its degradation. Consequently, GSTM4 regulates lipid synthesis, as well as the proliferation and metastasis of PCa cells, by modulating ACLY stability.
Kang‐Ping Xiong, Fei Liu, Wang Wang, Gang Wang, Kai‐Yu Qian, Sheng Tu, Si‐Ming Chen, Hui‐Min Xu, Shan‐Shan Zhang, Yong Li, Xing‐Huan Wang, Hong Weng   +11 more
wiley   +1 more source

Integrated O2 and H2 Gas Therapy via Microneedle‐Assisted Photocatalytic Water Splitting for Accelerating Diabetic Full‐Thickness Skin Wound Healing

Advanced Science, EarlyView.
A concept of integrated O2 and H2 gas therapy is achieved using a gas‐producing material. PMP nanoparticles, fabricated from platinum, MIL‐101(Fe)‐NH2, and phosphotungstic acid, are integrated into bilayer gelatin methacryloyl microneedles for transdermal delivery. These microneedles enable integrated O2 and H2 gas therapy and promote wound healing via
Zesheng Chen, Yanchao Yu, Xingyuan Xiao, Wenwen Cheng, Ye Yang, Zhengyao Zhang, Wang Wang, Zhijun Zhou, Weikang Hu, Xiaolong Wang, Bing Li, Kwang Leong Choy, Yun Chen, Zijian Wang   +13 more
wiley   +1 more source

united-manufacturing-hub/united-manufacturing-hub: v0.14.0

<h1><a href="https://github.com/united-manufacturing-hub/united-manufacturing-hub/compare/v0.13.7...v0.14.0">0.14.0</a> (2024-05-23)</h1> <h3>Bug Fixes</h3> <ul> <li>go work vendor (<a href="https ...
kruegeralex, Matteo Danelon, Oto.Nak, fossabot, David Mackel, Ferdinand Linnenberg, JonaVo, Ricardo Christmann, Robert Feldmann, actions-user, Lukas Hennies, ONUR CAN KARAMAN, larswitte, Matthew Judijanto, Semantic Release Bot, Pascal Bro, AMINE AMAACH, Derek Tiffany, Arne, Patrick Melichar, chrisproch, felixmhofmann, Jeremy Theocharis   +22 more
core   +1 more source

Polymer Concepts in Cellular Function

Advanced Science, EarlyView.
Miao Yu, Shikha Dhiman, Dorothee Dormann, Frauke Gräter, Katja Luck, Friederike Schmid, Andreas Walther, Edward A. Lemke   +7 more
wiley   +1 more source

Macrophage RSAD2 Couples mtDNA Synthesis With a Self‐Amplifying Inflammatory Circuit to Orchestrate Tissue Repair

Advanced Science, EarlyView.
Macrophage RSAD2 dually regulates CMPK2—the rate‐limiting enzyme for mitochondrial DNA synthesis—by suppressing its ubiquitination and promoting its phosphorylation via Csnk2a2 recruitment. This amplifies mtDNA production, which simultaneously activates a cGAS‐STING‐IRF3‐RSAD2 feedforward loop and the NLRP3 inflammasome, driving a self‐sustaining ...
Haomiao Yuan, Shukui Du, Chunfei Li, Xinjie Li, Shuyang Mu, Anran Qu, Hengxu Yan, Chongchong Xu, Jinnong Yang, Jingkai Sun, Yijun Wang, Jiayang Xiao, Fuyuan Zhang, Linlin Wang, Tiegang Li, Rui Zhao, Dawei Guan   +16 more
wiley   +1 more source

united-manufacturing-hub/united-manufacturing-hub: v0.15.0

<h1><a href="https://github.com/united-manufacturing-hub/united-manufacturing-hub/compare/v0.14.0...v0.15.0">0.15.0</a> (2024-06-07)</h1> <h3>Bug Fixes</h3> <ul> <li>qoutes (<a href="https://github.com ...
kruegeralex, Matteo Danelon, Oto.Nak, fossabot, David Mackel, Ferdinand Linnenberg, JonaVo, Ricardo Christmann, Robert Feldmann, actions-user, Lukas Hennies, ONUR CAN KARAMAN, larswitte, Matthew Judijanto, Semantic Release Bot, Pascal Bro, AMINE AMAACH, Derek Tiffany, Arne, Patrick Melichar, chrisproch, felixmhofmann, Jeremy Theocharis   +22 more
core   +1 more source

2025 National Food Hub Survey (Executive Summary) [PDF]

This executive summary presents key findings from the sixth National Food Hub Survey conducted by the Michigan State University Center for Regional Food Systems (CRFS), capturing food hub experiences during the 2024 calendar year.
Jude Barry, Sam Stokes, Kathryn Colasanti   +2 more
core   +1 more source

Glucose and Glutamine Deprivation Promotes Breast Cancer Lung Metastasis via BRD4‐Dependent Enhancer Activation

Advanced Science, EarlyView.
To model a nutrient‐restricted tumor microenvironment, breast cancer cells were adapted to low glucose and glutamine levels. In the adapted cells, BRD4‐driven enhancer activation increases pro‐invasive EDN1 expression, facilitated by ATF3/c‐JUN and reinforced by enhancer RNA.
Poshan Yugal Bhattarai, Arathy Vasukutty, Yujin Na, Sung‐Chul Lim, Hong Seok Choi   +4 more
wiley   +1 more source

Investigating capabilities of Food Hubs in short food supply chains

The International Review of Retail, Distribution and Consumer Research
Food Hubs (FHs) have been presented as a possible intermediary increasing competitive advantage of SFSCs. However, research on the capabilities of FHs related to sustainability indicators is limited. This study aims to investigate the capabilities of FHs and its relation to sustainability by conducting explorative case studies in Sweden.
Marije Renkema-Singh, Per Hilletofth
openaire   +3 more sources

Sex‐ and Time‐Resolved Physiological and Gut Ecosystem Responses to a Food‐Grade Microbiome‐Targeted Intervention in Collegiate Endurance Athletes

Advanced Science, EarlyView.
In collegiate endurance athletes, a 6‐week randomized CPYE intervention yielded time‐ and sex‐dependent shifts in field‐based cardiorespiratory, metabolic, and redox indices, accompanied by changes in gut multi‐omics profiles. An exploratory extension during intensified training generates hypotheses warranting future validation.
Meng Zhang, Le Ge, Kaiyang Liu, Yanrong Liu, Guolin Zhao, Lai‐Yu Kwok, Zheng Sun, Zhihong Sun, Wenyi Zhang   +8 more
wiley   +1 more source