Results 251 to 260 of about 799,910 (289)

Glutamine Deprivation Triggers Tribbles Homolog 3 Dependent G‐Quadruplex Resolution to Maintain DNA Repair and Tumor Survival

Advanced Science, EarlyView.
Glutamine deprivation triggers transient DNA damage yet activates adaptive repair in hepatocellular carcinoma cells. We identify TRIB3 as a stress‐induced nuclear scaffold that associates with DDX5 and G‐quadruplex DNA atBRCA1 andRAD51AP1 promoters. TRIB3 loss increases G4 accumulation, suppresses HR gene transcription, elevates γ‐H2A.X, and sensitizes
Qiang Ji, Xuedan Sun, Zhangran Sun, Mengfan Li, Xinyu Cheng, Shuai Tian, Rick F. Thorne, Jinming Li, Guangzhi Liu, Mian Wu, Xiaoying Liu   +10 more
wiley   +1 more source

Cis‐ and Trans‐Regulatory Factors Independently Shape Phenotypic Heterogeneity of Retinitis Pigmentosa

Advanced Science, EarlyView.
A zebrafish model carrying an identical human RHO S334X allele reveals two independent genetic layers shaping retinitis pigmentosa (RP) severity: a protective 3‐bp cis‐regulatory insertion that attenuates transgene expression, and a dominant trans‐acting modifier that restores a severe phenotype.
Cong Cui, Kotone Nakagawa, Takumi Tateno, Ayaka Dan, Dexin Meng, Yoshihiro Omori, Soma Tomihara, Suzuri Okamoto, Shigeru Sato, Motokazu Tsujikawa   +9 more
wiley   +1 more source

The impact of deprivation and neighbourhood food environments on home food environments, parental feeding practices, and child eating behaviours, food preferences and BMI: The Family Food Experience Study-London

Smith A, Kininmonth A, Tommerup K, Boniface D, Gericke C, Denning T, Summerbell C, Vogel C, Llewellyn C.   +8 more
europepmc   +1 more source

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Food preferences in families

Appetite, 1988
Preferences for a wide variety of foods were examined in families: 77 students, plus their siblings, mothers and fathers, for a total of 241 subjects. The food preferences of family members were more similar than would be expected by chance. However, this occurred entirely in the comparisons between spouses and between female family members.
A W, Logue, C M, Logue, R G, Uzzo, M J, McCarty, M E, Smith   +4 more
openaire   +2 more sources

Psychobiology of food preferences

International Journal of Obesity, 2001
Investigations with laboratory animals can reveal much about the basic psychobiological determinants of food preference and diet-induced overeating. When offered a choice of foods, rats typically prefer high-fat and/or high-sugar food items over their nutritionally balanced chow diet.
openaire   +2 more sources

Food Intake and Food Preference

2013
The biologic drive to eat results from complex neural and hormonal systems. The selection of one food over another is also complex, a process involving many factors including food availability, social and cultural norms, economic, biologic, and cognitive elements.
Stephanie Stein, Elizabeth Lamos, Michael Quartuccio, Sruti Chandraskaran, Nicole Ionica, Nanette Steinle   +5 more
openaire   +1 more source

Conditioned Food Preferences

1992
Publisher Summary This chapter explores that humans have receptors for four basic tastes: salt, sour, bitter, and sweet. Initial affective reactions to these four tastes appear to be genetically mediated. Initial reaction to the four basic tastes appears to be genetically mediated, in omnivores such as rats and humans most food preferences are ...
openaire   +1 more source

DEVELOPMENT OF FOOD PREFERENCES

Annual Review of Nutrition, 1999
▪ Abstract  Using a developmental systems perspective, this review focuses on how genetic predispositions interact with aspects of the eating environment to produce phenotypic food preferences. Predispositions include the unlearned, reflexive reactions to basic tastes: the preference for sweet and salty tastes, and the rejection of sour and bitter ...
openaire   +2 more sources

Determination of predator food preferences

Journal of Theoretical Biology, 1970
Abstract A definition of food preference is developed which is valid over a wide range of predation conditions. The definition agrees with intuitive ideas about preference and readily lends itself to experimental measurement. It implicitly takes into account the ease or difficulty of capture of the various prey species available to the predator ...
D J, Rapport, J E, Turner
openaire   +2 more sources