Results 81 to 90 of about 676,390 (361)
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li+10 more
wiley +1 more source
Health protection and food preservation by gamma irradiation [PDF]
Results of several major studies on food systems for space missions beginning with Apollo 12 through Apollo-Soyuz and investigations of the application of irradiation to food for manned space flight are reported. The study of flight food systems involved
core +1 more source
Agro forestry systems and food security among smallholder farmers of the Brazilian Amazon: A strategy for environmental global crisis [PDF]
The Amazon is known for its environmental importance for the climatic equilibrium, for its abundance and richness in biodiversity and its preservation is important to reduce global heating. Nevertheless, little research has analysed the possible positive
Abreu, Dr. Santiago de Lucimar+1 more
core
HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang+6 more
wiley +1 more source
Variability of characteristic components of aronia
The variability of characteristic components of aronia (Aronia melanocarpa, black chokeberry) and to evaluate the chemical composition and quality of aronia products in order to complete the already available data and to facilitate authentication of ...
Jitka ŠNEBERGROVÁ+5 more
doaj +1 more source
Leader's guide : food preservation [PDF]
To be used with 4-H Club circulars 33, 40 ...
core +2 more sources
In vitro cancer models are advantageous for studying important processes such as tumorigenesis, cancer growth, invasion, and metastasis. The complexity and biological relevance increase depending on the model structure, organization, and composition of materials and cells.
Kyndra S. Higgins+2 more
wiley +1 more source
Does Targeting a Designated Area Crowd out the other Preservation Programs’ Efforts? [PDF]
Maryland has introduced a number of land preservation programs over the past 40 years to permanently preserve resource lands. Although new programs can increase the number of acres being preserved, they might have unintended impact on land preservation ...
Liu, Xiangping, Lynch, Lori
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Fecal Microbiota Transplantation Modulates Th17/Treg Balance via JAK/STAT Pathway in ARDS Rats
Fecal microbiota transplantation (FMT) alleviates lung and intestinal injury in lipopolysaccharide (LPS)‐induced acute respiratory distress syndrome (ARDS) in rats. This study demonstrates that FMT restores the balance between Th17 and Treg cells, inhibits the JAK/STAT pathway, and modulates cytokine levels, reducing inflammation and lung damage. These
Dongwei Zhang+8 more
wiley +1 more source