Results 71 to 80 of about 3,757,307 (300)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Post-hatch fasting and infectious bronchitis vaccination affect growth, gastrointestinal development, and morphometric parameters of the small intestine of broiler breeders up to three weeks of age

Revista Brasileira de Zootecnia
The influence of fasting and vaccination against infectious bronchitis (IB) on growth, gastrointestinal development, and morphometric parameters of the small intestine of newborn broiler breeders was investigated. Weight gain (WG), feed conversion ratio (
Miguel Frederico Fernandez-Alarcon, Fernando Augusto de Souza, Daniel Mendes Borges Campos, Fabricio Hirota Hada, Wedson Carlos Lima Nogueira, Marcos Macari, Luiz Roberto Furlan, Renato Luis Furlan   +7 more
doaj   +1 more source

Seminiferous epithelium of rats with food restriction and carbon tetrachloride-induced cirrhosis

International Brazilian Journal of Urology, 2006
OBJECTIVE: Analyze the changes in the seminiferous epithelium in rats with carbon tetrachloride-induced cirrhosis (CCl4). MATERIALS AND METHODS: Forty-eight male Wistar rats aged 45-50 days, weighing 150-180 grams were used.
Marilise M. Horn, Ana R. Ramos, Leonardo Winkelmann, Ursula S. Matte, Helena A. Goldani, Themis R. Silveira   +5 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Food restriction promotes damage reduction in rat models of type 2 diabetes mellitus.

PLoS ONE, 2018
There are several animal models of type 2 diabetes mellitus induction but the comparison between models is scarce. Food restriction generates benefits, such as reducing oxidative stress, but there are few studies on its effects on diabetes. The objective
Carlos Vinicius Dalto da Rosa, Jéssica Men de Campos, Anacharis Babeto de Sá Nakanishi, Jurandir Fernando Comar, Isabela Peixoto Martins, Paulo Cézar de Freitas Mathias, Maria Montserrat Diaz Pedrosa, Vilma Aparecida Ferreira de Godoi, Maria Raquel Marçal Natali   +8 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Meat quality of castrated and non-castrated Santa Ines lambs subjected to food restriction

Semina: Ciências Agrárias, 2016
This study aimed to evaluate the quality of meat of castrated and non-castrated Santa Ines lambs submitted to food restriction. Were used 30 lambs, 15 castrated and 15 non-castrated, about two months of age and average initial body weight of 13.00 ± 1.49
Dayanne Lima de Sousa, Patrícia Guimarães Pimentel, Elisabeth Mary Cunha da Silva, Elzânia Sales Pereira, Assis Rubens Montenegro, Ana Cláudia Nascimento Campos, Ivone Yurika Mizubuti, Adrielle Albuquerque dos Santos   +7 more
doaj   +1 more source

Food Restriction-Induced Changes in Gonadotropin-Inhibiting Hormone Cells are Associated with Changes in Sexual Motivation and Food Hoarding, but not Sexual Performance and Food Intake

Front. Endocrin., 2011
We hypothesized that putative anorectic and orexigenic peptides control the motivation to engage in either ingestive or sex behaviors, and these peptides function to optimize reproductive success in environments where energy fluctuates.
C. M. Klingerman, Wilbur P. Williams, Jessica Simberlund, N. Brahme, A. Prasad, J. E. Schneider, L. Kriegsfeld   +6 more
semanticscholar   +1 more source