Results 41 to 50 of about 1,281,336 (313)

Assessing Cognitive Functioning in Children With Brain Tumors: Interaction of Neighborhood Social Determinants of Health and Neurological Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background This study investigated how neighborhood‐level social determinants of health (SDOH), including redlining and neurological risk, interact to influence cognitive outcomes in children treated for brain tumors (CTBT). Methods A retrospective chart review of 161 CTBT aged 5–17 was conducted.
Alannah R. Srsich, Manali Zope, Peter M. Fantozzi, Cassie N. Kline, Iris Paltin, Matthew C. Hocking   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Research on the application of big data in food safety supervision risk early warning

Shipin yu jixie, 2022
As an important part of modern food safety governance system, food safety risk early warning fully embodies the scientific principle of "prevention first, risk management, whole process control and social co governance".
DU Lin, WEN Sheng-jun, YUAN Gang
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Role of risk analysis and risk communication in food safety management [PDF]

, 2017
Concept of “risk analysis” in food safety management needs to be understood to assess, manage, and communicate risks for proper implementation of food safety policies, food laws, and standards, in a country. Science-based approaches, which are an integral part of risk analysis to improve modern food safety systems, are intimately linked to processes ...
openaire   +1 more source

An assessment of food safety information provision for UK chemotherapy patients to reduce the risk of foodborne infection [PDF]

, 2017
Objectives: Given the increased risk of foodborne infection to cancer patients receiving chemotherapy treatment, and the risk of listeriosis reportedly five-times greater to this immunocompromised patient group, there is a need to ensure the ...
Evans, Ellen W., Redmond, Elizabeth
core   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Wildlife as sentinel of antimicrobial resistance in Klebsiella spp. with genomic insights into Klebsiella pneumoniae in Northern Italy

Frontiers in Microbiology
IntroductionAntimicrobial resistance (AMR) is a global concern, particularly worsened by the spread of multidrug-resistant (MDR) bacteria such as Klebsiella pneumoniae.MethodsThis study investigated the presence of extended-spectrum β-lactamase (ESBL ...
Maria Sampieri, Lia Bardasi, Silvia Bonardi, Ilaria Menozzi, Alessandra Dodi, Erika Scaltriti, Giorgio Galletti, Elisa Massella, Cristina Bacci, Martina Rega, Mauro Conter   +10 more
doaj   +1 more source

A Study on Food Safety Risk Analysis under the Condition of Traditional Agriculture [PDF]

Journal of Risk Analysis and Crisis Response (JRACR), 2011
With the development of economy, the problem of food safety has caused extensive concern. Agricultural production node is on the front of the food safety management chain.
Jingyuan Yin, Haiyan Gao, Wei Pei
doaj   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source