Results 51 to 60 of about 7,287,909 (247)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
A sensitive method for electrochemical determination of molybdenum (VI) in plant foodstuff samples using Ni0.5Zn0.5Fe2O4 nanocomposite modified carbon paste electrode [PDF]
Nanochemistry Research, 2016 In the present study, a new chemically modified carbon paste electrode (CPE) is constructed for rapid, accurate, simple, highly sensitive, and selective determination of Mo (VI) using differential pulse voltammetry.
Abbas Afkhami +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Applications of Metal-Organic Frameworks in Food Sample Preparation
Molecules, 2018 Food samples such as milk, beverages, meat and chicken products, fish, etc. are complex and demanding matrices. Various novel materials such as molecular imprinted polymers (MIPs), carbon-based nanomaterials carbon nanotubes, graphene oxide and metal ...
Natalia Manousi +3 more
doaj +1 more source
Recent Materials Developed for Dispersive Solid Phase Extraction
Molecules, 2020 Solid phase extraction (SPE) is an analytical procedure developed with the purpose of separating a target analyte from a complex sample matrix prior to quantitative or qualitative determination.
Piotr Ścigalski, Przemysław Kosobucki
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Determination of Trace Copper(II) in Food Samples by Flame Atomic Absorption Spectrometry after Cloud Point Extraction [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 2011 A new method for the determination of trace copper(II) in food samples by Cloud Point Extraction(CPE) combined with Flame Atomic Absorption Spectrometry(FAAS) is presented and evaluated.
Guoqiang Xiang +4 more
doaj
Química Nova, 2011 A sensitive preconcentration procedure for spectrophotometeric determination of aluminum was developed. Aluminum as aluminon complex is adsorbed on microcrystalline naphthalene.
Mohammad Reza Fathi +2 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source