Results 71 to 80 of about 5,097,588 (308)

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

Aide memoire for food supplement establishment inspections

open access: yes, 2012
Authority of Ireland (FSAI), in collaboration with the environmental health service (EHS), to aid environmental health officers (EHOs) carry out official control inspections in food supplement establishments.
Food Safety Authority of Ireland (FSAI)
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Impact of Spirulina sp. on growth and food intake in Danio rerio Hamilton, 1822

open access: yesیافته‌های نوین در علوم زیستی, 2015
Danio rerio Hamilton, 1822 is one of the commercial ornamental fresh water fishes and living in tropical zones, of considerable economic value in our country. This study aimed at investigating the impact of Spirulina sp.
Majid Beiranvand   +2 more
doaj  

Information on nutrition and health claims and food supplements

open access: yes, 2010
This document is support material for the training programme on the regulation of nutrition and health claims and food supplements in Ireland. The document provides an overview of the: – Nutrition labelling requirements – Framework of the nutrition ...
Food Safety Authority of Ireland (FSAI)
core  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Dietary supplements, guideline alignment and biochemical nutrient status in pregnancy: Findings from the Queensland Family Cohort pilot study

open access: yesMaternal and Child Nutrition
In high‐income nations, multiple micronutrient (MMN) supplementation during pregnancy is a common practice. We aimed to describe maternal characteristics associated with supplement use and daily dose of supplemental nutrients consumed in pregnancy, and ...
Linda A. Gallo   +11 more
doaj   +1 more source

Food Access and Food Security – An Empirical Analysis [PDF]

open access: yes
This paper analyzes the effect of access to different types of food outlets on households’ food insecurity levels. Two years (2004 and 2005) of Current Population Survey – Food Security Supplement data are matched with MSA-level data on store counts of ...
Li, Jing, Bonanno, Alessandro
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

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