Results 91 to 100 of about 430,952 (268)
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Frontiers in NutritionBackgroundThe global rise in type 2 diabetes (T2D) and obesity, driven by high-sugar snacks, underscores the need for low-calorie, fiber-enriched alternatives that attenuate postprandial glycemia while maintaining cultural appeal in date-consuming ...
Abdulmalik Alhuwaymil +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
BeneficiumThe escalation of geopolitical instability is causing a sharp increase in attention to issues of resource provision of the state and its regions. In particular, regional food supply is pivotal in shaping food security, as it is at the regional level ...
Xinyi Qian / Синьи Цянь
doaj +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Toward more sustainable food supply chains: insights from short food supply chains in Jordan
Frontiers in SustainabilityIntroductionShort Food Supply Chains (SFSCs) are promoted as a pathway to more sustainable agri-food systems. Jordan’s fresh-produce sector, which relies heavily on local markets, offers a valuable setting to examine how SFSCs support sustainability ...
Muna Abdulkareem +2 more
doaj +1 more source