Results 111 to 120 of about 398,530 (320)
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson+11 more
wiley +1 more source
Energetic closure of the spatially resolved global food system [PDF]
The global food system provides the energy that supports human metabolism, with complex spatial interdependencies between food production, transformation, and consumption. Empirical food system data for these global processes are often fragmented and inconsistent, with only certain components captured in spatially resolved formats.
arxiv
Understanding food inflation in India: A Machine Learning approach [PDF]
Over the past decade, the stellar growth of Indian economy has been challenged by persistently high levels of inflation, particularly in food prices. The primary reason behind this stubborn food inflation is mismatch in supply-demand, as domestic agricultural production has failed to keep up with rising demand owing to a number of proximate factors ...
arxiv
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen+12 more
wiley +1 more source
Evaluation nutrients of Turkish Snack Bars Based on Labeling and Web Page Information: A Qualitative Research [PDF]
Background: Snack bars, a globally popular food category, contain a diverse variety of ingredients and appeal to different dietary preferences. Even though snack alternatives are gaining prominence as viable options for promoting healthy dietary ...
İ. Öztürk Altuncevahir+2 more
doaj
A simulation-optimization framework for food supply chain network design to ensure food accessibility under uncertainty [PDF]
How to ensure accessibility to food and nutrition while food supply chains suffer from demand and supply uncertainties caused by disruptive forces such as the COVID-19 pandemic and natural disasters is an emerging and critical issue. Unstable access to food influences the level of nutrition that weakens the health and well-being of citizens. Therefore,
arxiv
Understanding and measuring mechanical signals in the tumor stroma
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz+3 more
wiley +1 more source