Results 111 to 120 of about 6,125,392 (393)

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

The current situation of EU’s food chain [PDF]

open access: yes
The sharp fluctuations in agricultural commodity and food prices at a time of great uncertainty about the economic outlook illustrate the need to improve the functioning of the European food supply chain with a view to enhancing its efficiency and ...
Balogh, Viktoria   +2 more
core   +1 more source

How COVID-19 may disrupt food supply chains in developing countries

open access: yes, 2020
COVID-19 is spreading through the developing world. Many low- and middle-income countries are now reporting growing numbers of cases and imposing rigorous lockdown regulations in response, which impact all aspects of the economy. How will COVID-19 affect
T. Reardon   +2 more
semanticscholar   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

The global food crisis : supply and demand revisited [PDF]

open access: yes, 2015
This study aims to show that the volatility in food prices between 2008 and 2011 cannot be explained merely by the market fundamentals of demand and supply. While global changes in demand and supply are bringing about radical changes to the food equation,
Sammut, Vince
core  

L’émergence d’un gouvernement humanitaire de la pauvreté nutritionnelle en Afrique de l’Ouest

open access: yesRevue d'anthropologie des connaissances, 2016
This article describes the role of quantification in the emergence of a humanitarian government of nutritional poverty through dairy products in West Africa between 1930 and 1980.
Samuel Pinaud
doaj   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Life Cycle Assessment across the Food Supply Chain [PDF]

open access: yes, 2009
The environmental impact is one of the major pillars of concerns when addressing the sustainability of food production and sustainable food consumption strategies.
Dalgaard, Randi   +5 more
core  

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

Developments in Global Food Prices [PDF]

open access: yes
Global food prices have increased significantly since the early 2000s, reversing the long-run trend decline in relative food prices over previous decades.
Emily Laing, Jamie Hall, Vanessa Rayner
core  

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