A qualitative risk assessment of factors contributing to foot and mouth disease outbreaks in cattle along the western boundary of the Kruger National Park [PDF]
, 2009 Between November 2000 and the end of 2007, five outbreaks of foot and mouth disease (FMD) occurred in cattle in the area adjacent to the Kruger National Park (KNP) in the north-eastern corner of South Africa.
Bengis, R.G. +6 more
core +1 more source
mBio, 2020 Effective control of a disease relies on comprehensive understanding of how transmission occurs, in order to design and apply effective control measures. Foot-and-mouth disease virus (FMDV) is primarily spread by direct contact between infected and naive
C. Colenutt +7 more
semanticscholar +1 more source
Tolerance to mutations in the foot-and-mouth disease virus integrin-binding RGD region is different in cultured cells and in vivo and depends on the capsid sequence context. [PDF]
, 2008 Engineered RNAs carrying substitutions in the integrin receptor-binding Arg-Gly-Asp (RGD) region of foot-and-mouth disease virus (FMDV) were constructed (aa 141-147 of VP1 capsid protein) and their infectivity was assayed in cultured cells and suckling
Baranowski, Eric +4 more
core +3 more sources
Environmental Persistence of Foot and Mouth Disease Virus Applied to Endemic Regions.
Transboundary and Emerging Diseases, 2020 The consequences of foot-and-mouth disease impact regional economies and food security through animal mortality and morbidity, trade restrictions, and burdens to veterinary infrastructure.
Sara Mielke, R. Garabed
semanticscholar +1 more source
The Structure of Foot-and-Mouth Disease Virus
, 2005 Structural studies of foot-and-mouth disease virus (FMDV) have largely focused on the mature viral particle, providing atomic resolution images of the spherical protein capsid for a number of sero- and sub-types, structures of the highly immunogenic surface loop, Fab and GAG receptor complexes.
Fry, E, Stuart, D, Rowlands, D
openaire +4 more sources
Evolution of foot-and-mouth disease virus intra-sample sequence diversity during serial transmission in bovine hosts [PDF]
, 2013 RNA virus populations within samples are highly heterogeneous, containing a large number of minority sequence variants which can potentially be transmitted to other susceptible hosts. Consequently, consensus genome sequences provide an incomplete picture
Haydon, D.T. +6 more
core +2 more sources
Transboundary and Emerging Diseases, 2020 Foot-and-mouth disease (FMD) is a highly contagious viral disease of cloven-hooved animals. Global outbreaks have highlighted the significant economic, trade, psychosocial and animal welfare impacts that can arise from the detection of disease in ...
C. Bath +14 more
semanticscholar +1 more source
Airborne excretion of foot-and-mouth disease virus [PDF]
Epidemiology and Infection, 1969 SUMMARYA large-volume sampler was used to recover virus excreted as aerosol by cattle, sheep and pigs infected with foot-and-mouth disease. Pigs were found to excrete virus to a maximum of 104.7ID 50 per animal per hour and sheep and cattle to a maximum of 103.2ID 50.
R. F. Sellers, J. Parker
openaire +3 more sources
Foot-and-Mouth Disease Impact on Smallholders - What Do We Know, What Don't We Know and How Can We Find Out More? [PDF]
, 2016 Foot-and-mouth disease (FMD) endemic regions contain three-quarters of the world's FMD susceptible livestock and most of the world's poor livestock keepers. Yet FMD impact on smallholders in these regions is poorly understood.
Abao +80 more
core +1 more source
Cell Death and Disease, 2020 The RIG-I-like receptor (RLR) melanoma differentiation-associated gene 5 (MDA5) plays a key role in triggering innate antiviral response during infection by RNA viruses.
Miguel Rodríguez Pulido +3 more
semanticscholar +1 more source