Results 11 to 20 of about 214,010 (272)

Detection of Foot-and-Mouth Disease Virus in the Absence of Clinical Disease in Cattle and Buffalo in South East Asia

Frontiers in Veterinary Science, 2021
Foot-and-mouth disease virus (FMDV) is widespread throughout much of the world, including parts of South East Asia. Surveillance is often limited in endemic areas, relying predominantly on passive outbreak reporting. As part of the World Organisation for
Kelly Buckle, Rudolfo Bueno, Andrew McFadden, Mary van Andel, Richard Spence, Carolyn Hamill, Wendi Roe, Emilie Vallee, Fernanda Castillo-Alcala, Ronel Abila, Blesilda Verin, Bolortuya Purevsuren, Ashish Sutar, Htun Htun Win, Myo Thiha, Khin Ohnmar Lwin, Syseng Khounsy, Sengxay Phonthasy, Viliddeth Souriya, Chattouphone Keokhamphet, Jonathan Arzt, Anna Ludi, Valérie Mioulet   +22 more
doaj   +1 more source

Experimental Infection of Foot and Mouth Disease in Indian Sheep and Goats

Frontiers in Veterinary Science, 2020
Foot-and-mouth disease (FMD) is an economically important contagious disease of livestock mainly cattle, buffalo, sheep, goats, and pig. There is limited data available on pathogenesis of foot and mouth disease in goats. In the study, the sheep and goats
Madhanmohan Muthukrishnan, Nagendrakumar Singanallur Balasubramanian, Srinivasan Villuppanoor Alwar   +2 more
doaj   +1 more source

Phase Ib study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis

Hepatology, EarlyView., 2022
Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou, Yongkun Sun, Wen Zhang, Jiajia Yuan, Zhi Peng, Wei Wang, Jifang Gong, Lin Yang, Yanshuo Cao, Hong Zhao, Chao Chen, Weifeng Wang, Lin Shen, Aiping Zhou   +13 more
wiley   +1 more source

Risk of foot-and-mouth disease spread due to sole occupancy authorities and linked cattle holdings [PDF]

, 2012
Livestock movements in Great Britain are well recorded, have been extensively analysed with respect to their role in disease spread, and have been used in real time to advise governments on the control of infectious diseases.
O'Hare, Anthony, Orton, R., Kao Rowland R., Colin P D Birch, Kao, Rowland R, Orton, Richard, Bessell, Paul R, Birch, Colin P. D., O'Hare, A., Colin P. D. Birch (126488), Richard J Orton, Orton Richard J., Orton, Richard J., Anthony O'Hare (116908), O'Hare Anthony, Paul R Bessell, Kao, R., Bessell, Paul R., Kao, Rowland R., Rowland R Kao, Bessell Paul R., Bessell, P., Rowland R. Kao (116940), Richard J. Orton (116918), Paul R. Bessell (169949), Birch Colin P. D., Anthony O'Hare, Birch, Colin P D   +27 more
core   +1 more source

Heterogeneity and Recombination of Foot-and-Mouth Disease Virus during Multi-Strain Coinfection of Cattle

mSphere, 2023
Superinfection of cattle persistently infected with foot-and-mouth disease virus (FMDV), with a heterologous FMDV strain has been shown to generate novel recombinant viruses.
Carolina Stenfeldt, Ian Fish, Haillie C. Meek, Jonathan Arzt   +3 more
doaj   +1 more source

Foot-and-mouth disease virus

Comparative Immunology, Microbiology and Infectious Diseases, 2002
Foot-and-mouth disease virus (FMDV) is an aphthovirus of the family Picornaviridae and the etiological agent of the economically most important animal disease. As a typical picornavirus, FMD virions are nonenveloped particles of icosahedral symmetry and its genome is a single stranded RNA of about 8500 nucleotides and of positive polarity.
Domingo, Esteban, Escarmís, Cristina, Sobrino, Francisco, Baranowski, Eric   +3 more
openaire   +5 more sources

Inhibition of the foot-and-mouth disease virus subgenomic replicon by RNA aptamers. [PDF]

, 2014
We have previously documented the inhibitory activity of RNA aptamers to the RNA-dependent RNA polymerase of foot-and-mouth disease virus (3D(pol)). Here we report their modification and use with a subgenomic replicon incorporating GFP (pGFP-PAC replicon)
Forrest, S, Lear, Z, Ryan, M., Herod, M, Forrest, S., Ryan, M, Stonehouse, N.J., Rowlands, DJ, Herod, M.R., Stonehouse, NJ, Lear, Z., Rowlands, D.J.   +11 more
core   +1 more source

Induction of Partial Protection against Foot and Mouth Disease Virus in Guinea Pigs by Neutralization with the Integrin β6-1 Subunit

Viruses, 2013
The mechanism by which the foot-and-mouth disease virus (FMDV) initiates infection of cells is thought to involve the attachment of the viral capsid to host integrins on the surface of target cells.
Zhidong Zhang, Haixue Zheng, Lv Lv, Jijun He, Qiong Wu, Weijun Cao, Fan Yang, Jianhong Guo, Yingjun Sun, Yan Zhang   +9 more
doaj   +1 more source

Efficient production of foot-and-mouth disease virus empty capsids in insect cells following down regulation of 3C protease activity [PDF]

, 2013
Foot-and-mouth disease virus (FMDV) is a significant economically and distributed globally pathogen of Artiodactyla. Current vaccines are chemically inactivated whole virus particles that require large-scale virus growth in strict bio-containment with ...
Owens, Ray, Paramasivam, S, Kotecha, A, Wilsden, G, Parida, Satya, Paton, David, Ren, Junyuan, Al-Khalil, Tara, Belsham, Graham J., Lomonossoff, GP, Li, Yanmin, Belsham, GJ, Loureiro, S, Kotecha, Abhay, Belsham, Graham, Owens, R, Stuart, David I, Lomonossoff, George P., Porta, C, Xu, X, Parida, S, Lomonossoff, George P, Burman, Alison, Paton, D, Jones, IM, Curry, S, Blesham, Graham J., Paramasivam, Saravanan, Xu, Xiaodong, Stuart, DI, Charleston, Bryan, Jackson, T, Charleston, B, Burman, A, Jones, Ian M., Porta, Claudine, Ren, J, Stuart, David I., Fry, E, Stuart, David, Jones, Ian M, Ferris, N, Ferris, Nigel, Loureiro, Silvia, Belsham, Graham J, Curry, Stephen, Jackson, Terry, Al-Khalil, T, Li, Y, Fry, Elizabeth, Wilsden, Ginette   +50 more
core   +1 more source

Evaluation of Gaussia luciferase and foot-and-mouth disease virus 2A translational interrupter chimeras as polycistronic reporters for transgene expression

BMC Biotechnology, 2017
Background The Gaussia princeps luciferase is used as a stand-alone reporter of transgene expression for in vitro and in vivo expression systems due to the rapid and easy monitoring of luciferase activity.
Michael Puckette, Thomas Burrage, John G. Neilan, Max Rasmussen   +3 more
doaj   +1 more source