Results 31 to 40 of about 214,010 (272)

Tolerance to mutations in the foot-and-mouth disease virus integrin-binding RGD region is different in cultured cells and in vivo and depends on the capsid sequence context. [PDF]

, 2008
Engineered RNAs carrying substitutions in the integrin receptor-binding Arg-Gly-Asp (RGD) region of foot-and-mouth disease virus (FMDV) were constructed (aa 141-147 of VP1 capsid protein) and their infectivity was assayed in cultured cells and suckling
Pulido, M. R., Gutiérrez-Rivas, M, Baranowski, Eric, Sáiz, M, M. Gutierrez-Rivas, Sobrino, Francisco, F. Sobrino, M. Saiz, Sobrino Castelló, Francisco, Gutiérrez-Rivas, Monica, Pulido, Miguel R, M. R. Pulido, Sobrino, F, Pulido, Mr, Sáiz, Margarita, E. Baranowski   +15 more
core   +1 more source

Topographic determinants of foot and mouth disease transmission in the UK 2001 epidemic [PDF]

, 2006
Background A key challenge for modelling infectious disease dynamics is to understand the spatial spread of infection in real landscapes. This ideally requires a parallel record of spatial epidemic spread and a detailed map of susceptible host density ...
Savill Nicholas J, MatthewJ Keeling, Rob Deardon, Grenfell Bryan T, Shaw, Darren J; id_orcid, Savill, Nicholas J., Shaw Darren J, Deardon, Rob, Deardon Rob, Brooks, Stephan P., NicholasJ Savill, Woolhouse Mark EJ, Woolhouse, Mark E. J., Brooks, Stephen P, Grenfell, Bryan T., Keeling Matthew J, MichaelJ Tildesley, Woolhouse, Mark E J; id_orcid, BryanT Grenfell, Tildesley Michael J, Brooks Stephen P, Keeling, Matthew James, Tildesley, Michael J., Keeling, Matthew J, Tildesley, Michael J, Grenfell, Bryan T, MarkEJ Woolhouse, StephenP Brooks, Shaw, Darren J., Savill, Nicholas J, DarrenJ Shaw   +30 more
core   +1 more source

In Vitro and in Vivo Antiviral Activity of Mizoribine Against Foot-And-Mouth Disease Virus

Molecules, 2019
Foot-and-mouth disease (FMD) is a highly contagious viral disease of cloven-hoofed animals, which has significant economic consequences in affected countries. As the currently available vaccines against FMD provide no protection until 4−7 days post-
Shi-Fang Li, Mei-Jiao Gong, Yue-Feng Sun, Jun-Jun Shao, Yong-Guang Zhang, Hui-Yun Chang   +5 more
doaj   +1 more source

Vaccination against Foot-and-mouth disease : do initial conditions affect its benefit? [PDF]

, 2013
When facing incursion of a major livestock infectious disease, the decision to implement a vaccination programme is made at the national level. To make this decision, governments must consider whether the benefits of vaccination are sufficient to ...
Auty, Harriet K., Michael J. Tildesley (123224), Porphyre Thibaud, Tildesley Michael J., Auty, HK, Tildesley,, MJ, Harriet K. Auty (333828), George J. Gunn (467023), Woolhouse, Mark E. J., Porphyre, Thibaud, Auty Harriet K., Thibaud Porphyre (124835), Porphyre, T, Michael J Tildesley, Auty, Harriet K, Gunn, GJ, Woolhouse, Mark E J; id_orcid, Woolhouse Mark E. J., Mark E J Woolhouse, Gunn George J., Harriet K Auty, Woolhouse, MEJ, Woolhouse, M. E. J., (Mark E. J.), Tildesley, Michael J., Mark E. J. Woolhouse (163944), Colizza, Vittoria, Tildesley, Michael J, Thibaud Porphyre, George J Gunn, Gunn, George J., Gunn, George J   +30 more
core   +1 more source

Bioinformatics based design of thermostable virus-like particles-based vaccine for foot-and-mouth disease serotype A and in-vivo evaluation in guinea pigs

Frontiers in Cellular and Infection Microbiology
BackgroundFoot-and-mouth disease (FMD) is a contagious disease affecting cloven footed animals. Existing vaccines although effective, has limitations of short immunity, needs cold chain maintenance, high biosafety levels facilities for production and ...
Deepak Praveen Raj Selvaraj, Paramasivam Saravanan, Aparna Madhavan, Das Adwitiya, Chandan Tilak, Beeragere Parameshwaraiah Sreenivasa, Shreya Gopinath, Sekar Elackiya, Saravanamuthu Thiyagarajan, Pallab Chaudhuri   +9 more
doaj   +1 more source

Complex Circulation of Foot-and-Mouth Disease Virus in Cattle in Nigeria

Frontiers in Veterinary Science, 2020
Nigeria is a large densely populated country in West Africa. Most of its livestock is raised in a pastoralist production system with typical long distance migration in search of water and feed.
Hussaini G. Ularamu, David J. Lefebvre, Andy Haegeman, Yiltawe S. Wungak, David O. Ehizibolo, David D. Lazarus, Annebel R. De Vleeschauwer, Kris De Clercq   +7 more
doaj   +1 more source

Airborne excretion of foot-and-mouth disease virus [PDF]

Epidemiology and Infection, 1969
SUMMARYA large-volume sampler was used to recover virus excreted as aerosol by cattle, sheep and pigs infected with foot-and-mouth disease. Pigs were found to excrete virus to a maximum of 104.7ID 50 per animal per hour and sheep and cattle to a maximum of 103.2ID 50.
R F, Sellers, J, Parker
openaire   +2 more sources

Differentiation of Foot-and-Mouth Disease-Infected pigs from Vaccinated Pigs Using Antibody-Detecting Sandwich ELISA

, 2011
The presence of serum antibodies for nonstructural proteins of the foot-and-mouth disease virus (FMDV) can differentiate FMDV-infected animals from vaccinated animals.
Ming-Hwa JONG, Dekker, A., Wen-Bin CHUNG, Lin, Y.L., Fan LEE, Yeou-Liang LIN, Chen, T.H., Ming-Chang LEE, Chu-Hsiang PAN, Hsiang-Jung TSAI, Aldo DEKKER, Lee, M.C., Tsai, H.J., Tsu-Han CHEN, Chin-Cheng HUANG, Chung, W.B., Pan, C.H., Jong, M.H., Huang, C.C., Lee, F.   +19 more
core   +1 more source

Preliminary evaluation of a novel serotype O foot-and-mouth disease mRNA vaccine

Frontiers in Microbiology
Foot-and-mouth disease virus (FMDV) is one of the most significant animal pathogens worldwide, severely impacting the health and productivity of pigs, cattle, sheep, and other ungulates.
Jingang Zhao, Jingang Zhao, Peng Xiao, Aiguo Xin, Aiguo Xin, Heran Zhu, Heran Zhu, Hao Wang, Jinlong Xiao, Hong Gao, Hong Gao   +10 more
doaj   +1 more source

Comparative expression analysis of inflammatory and immune-related genes in cattle during acute infection with foot-and-mouth disease virus in Egypt

Journal of Veterinary Research, 2021
Foot-and-mouth disease is a highly infectious viral disease affecting all cloven-footed domestic animals. The three foot-and-mouth disease virus (FMDV) serotypes A, O and SAT2 are at present the greatest threat to susceptible animals in Egypt. The aim of
El Nahas Abeer F., Abd El Naby Walaa S.H., Khatab Shymaa A., Fergany Al-Zahraa A., Rashed Rashed R.   +4 more
doaj   +1 more source