Results 81 to 90 of about 87,043 (349)

Cross-sectional serological study to estimate foot-and-mouth disease virus non-structural protein antibodies in randomly sampled small ruminants and pigs in Haryana during 2019 and 2020

Indian Journal of Animal Sciences
Foot-and-mouth disease (FMD) is highly contagious and affects various cloven-hoofed animals including cattle, buffalo, sheep, goat and pig. This study investigates the prevalence of foot-and-mouth disease virus (FMDV) non- structural protein antibodies (
M ROUT, S DAHIYA, A LATHER, R AASAREY, J P TRIPATHY, S SUBRAMANIAM, J K MOHAPATRA , R P SINGH   +7 more
doaj   +1 more source

Pulmonary Delivery of siRNA Anti‐TNFα‐loaded Lipid Nanoparticles for Rapid Recovery in Murine Acute Lung Injury

Advanced Healthcare Materials, EarlyView.
In a murine model of acute lung injury, pulmonary administration of lipid nanoparticles carrying TNFα siRNA enables targeted delivery to immune cells. The study emphasises the importance of optimizing LNP distribution and delivery timing to improve therapeutic outcomes and develop emergency therapies for lung hyperinflammation.
Qinglin Wang, Jihana Achour, Laila Emam, Younes Louaguenouni, Catherine Cailleau, Françoise Mercier‐Nomé, Séverine Domenichini, Claudine Delomenie, Sezen Gul, Juliette Vergnaud, Nicolas Tsapis, Arnaud Mansart, Djillali Annane, Francois Fay, Elias Fattal   +14 more
wiley   +1 more source

Evaluation of immunogenicity and cross-reactive responses of  vaccines prepared from two chimeric serotype O foot-and-mouth disease viruses in pigs and cattle

Veterinary Research, 2022
Foot-and-mouth disease (FMD) remains a very serious barrier to agricultural development and the international trade of animals and animal products. Recently, serotype O has been the most prevalent FMDV serotype in China, and it has evolved into four ...
Pinghua Li, Shulun Huang, Jingjing Zha, Pun Sun, Dong Li, Huifang Bao, Yimei Cao, Xingwen Bai, Yuanfang Fu, Xueqing Ma, Kun Li, Hong Yuan, Jing Zhang, Zhixun Zhao, Jian Wang, Keqiang Zhang, Yingli Chen, Qiang Zhang, Shuyun Qi, Zaixin Liu, Zengjun Lu   +20 more
doaj   +1 more source

The Epidemiology of Hand, Foot and Mouth Disease in Asia

The Pediatric Infectious Disease Journal, 2016
Context: Hand, foot and mouth disease (HFMD) is a widespread pediatric disease caused primarily by human enterovirus 71 (EV-A71) and Coxsackievirus A16 (CV-A16). Objective: This study reports a systematic review of the epidemiology of HFMD in Asia.
W. M. Koh, T. Bogich, K. Siegel, Jing Jin, E. Y. Chong, C. Y. Tan, Mark I. C. Chen, P. Horby, A. Cook   +8 more
semanticscholar   +1 more source

Multifunctional Biomedical Devices with Closed‐Loop Systems for Precision Therapy

Advanced Healthcare Materials, EarlyView.
This review explores two major types of closed‐loop therapeutic systems: self‐sustained and externally triggered. It highlights recent advances in stimuli‐responsive materials, integrated bioelectronics, and data‐driven control strategies, offering insight into emerging strategies for personalized, responsive drug delivery.
Yixuan Leng, Rujie Sun
wiley   +1 more source

The long non-coding RNA LNC_000397 negatively regulates PRRSV replication through induction of interferon-stimulated genes

Virology Journal, 2022
Background Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most significant threats to the global swine industry. It is of great importance to understand viral-host interactions to develop novel antiviral strategies.
Jing Zhang, Lipeng Gan, Pu Sun, Jian Wang, Dong Li, Yimei Cao, Yuanfang Fu, Pinghua Li, Xingwen Bai, Kun Li, Xueqing Ma, Huifang Bao, Yingli Chen, Jie Zhang, Zaixin Liu, Zengjun Lu   +15 more
doaj   +1 more source

Time-series modelling and forecasting of hand, foot and mouth disease cases in China from 2008 to 2018

Epidemiology and Infection, 2019
Seasonal autoregressive-integrated moving average (SARIMA) has been widely used to model and forecast incidence of infectious diseases in time-series analysis. This study aimed to model and forecast monthly cases of hand, foot and mouth disease (HFMD) in
Changwei Tian, Haiyin Wang, Xia Luo
semanticscholar   +1 more source

Si Inhibited Osteoclastogenesis: The Role of Fe and the Fenton Reaction

Advanced Healthcare Materials, EarlyView.
Silicate (Si) inhibition of osteoclastogenesis, is mediated by Fe. Si chemical interactions with Fe inhibit the Fenton reaction and intercellular ROS availability. This reduction in ROS availability inhibits osteoclastogenesis. The addition of Fe, in Si‐inhibited osteoclast cultures, restores the Fenton reaction, and osteoclastogenesis.
Yutong Li, Adriana‐Monica Radu, Azadeh Rezaei, Joel Turner, Kaveh Shakib, Akiko Obata, Toshihiro Kasuga, Gavin Jell   +7 more
wiley   +1 more source

Calcium Chloride Treatment Enhances Antigen Production in Foot-and-Mouth Disease Vaccines for Serotypes SAT1 and SAT3

Vaccines
Foot-and-mouth disease (FMD) is a highly contagious viral infection causing acute and severe vesicular lesions in cattle and pigs, which has prompted global vaccination policies. This study presents a technique for enhancing antigen yield in SAT1 BOT and
Dohyun Kim, Sun Young Park, Gyeongmin Lee, Eun-Sol Kim, Jong-Sook Jin, Jae Young Kim, SooAh Lee, Jong-Hyeon Park, Young-Joon Ko   +8 more
doaj   +1 more source

Emerging Coxsackievirus A6 Causing Hand, Foot and Mouth Disease, Vietnam

Emerging Infectious Diseases, 2018
Hand, foot and mouth disease (HFMD) is a major public health issue in Asia and has global pandemic potential. Coxsackievirus A6 (CV-A6) was detected in 514/2,230 (23%) of HFMD patients admitted to 3 major hospitals in southern Vietnam during 2011–2015 ...
N. T. Anh, L. Nhu, H. Van, N. Hong, T. T. Thanh, V. Hang, N. Ny, L. A. Nguyet, T. Phuong, L. Nhan, N. T. Hung, T. H. Khanh, H. M. Tuan, H. Viet, Nguyen Tran Nam, D. C. Viet, P. Qui, B. Wills, Sarawathy Sabanathan, N. Chau, L. Thwaites, H. Rogier van Doorn, G. Thwaites, M. Rabaa, Le Van Tan   +24 more
semanticscholar   +1 more source