Results 111 to 120 of about 82,603 (308)

Construction of risk prediction model for recurrence of diabetic foot ulcer

Huli yanjiu, 2022
ObjectiveThis study aimed to investigate the current status and influencing factors of diabetic foot ulcer recurrence within 1 year after healing and to establish a risk prediction model.MethodsThe convenience sampling method was used to select patients ...
LYU Jing, YUAN Li, LI Rao, HUANG Fengmei
doaj  

Impact of foot progression angle modification on plantar loading in individuals with diabetes mellitus and peripheral neuropathy [PDF]

, 2016
AIMS: To determine if participants can reduce foot progression angle (FPA), and if FPA reduction decreases regional plantar stresses and forces in individuals with diabetes.
Bohnert, Kathryn L, Hastings, Mary K, Hollman, John H, Merriwether, Ericka N, Sinacore, David R, Strube, Michael J   +5 more
core   +2 more sources

Reprogramming M2b Macrophages via GPX1 Activation by Selenium Nanoparticles Attenuates Lupus Nephritis

Advanced Science, EarlyView.
SeZM NPs selectively target M2b macrophages through mannose–MRC1 (CD206) recognition, enhance GPX1 biosynthesis, and suppress mitochondrial ROS generation, oxidative stress, and JAK–STAT signaling. This dual regulation reduces pro‐inflammatory cytokine release, limits immune cell infiltration and fibrosis, and preserves renal function, providing a ...
Haoran Lv, Guanning Huang, Hongyu Li, Hanzhi Liang, Huajing Peng, Kefei Wu, Wenfang Chen, Dandan Zhang, Kexin Ma, Yufei Du, Siweier Luo, Yi Zhou, Haiping Mao, Wei Chen, Tianfeng Chen, Yiming Zhou, Qinghua Liu   +16 more
wiley   +1 more source

The Relationship between Controlling HbA1C and Infectious Foot Ulcer

مجله دانشکده پزشکی اصفهان, 2012
Background: One of the major risk factors of foot ulcer is uncontrolled diabetes mellitus (DM) or in fact uncontrolled HbA1C. The aim of this study was to evaluate the relationship between controlling HbA1C and foot ulcer.
Mohsen Meidani, Farzin Khorvash, Mohammad Reza Rajabpournikfam   +2 more
doaj  

Endothelial PDGF Signaling Dysregulation Impairs Testicular Interstitial Homeostasis in Diabetes

Advanced Science, EarlyView.
Testicular endothelial cells (TECs) function as central signaling hubs that coordinate interstitial homeostasis. Diabetes disrupts TEC‐derived PDGF signaling, silences the JUND‐MCL1 survival program in Leydig cells, and impairs peritubular function, leading to fibrosis and testosterone insufficiency.
Wenxiu Zhang, Kai Hong, Yanling Tang, Lina Cui, Xiaojian Lu, Jianxing Cheng, Yangyi Fang, Qiaoling Jiang, Ziyan Zhuang, Songzhan Gao, Hui Jiang, Qiang Liu, Jingtao Guo, Zhe Zhang, Xiaoyan Wang   +14 more
wiley   +1 more source

The Missing Link: the key to improved wound assessment [PDF]

, 2012
Clinicians discuss using Debrisoft to improve wound assessement, quality of life and cost ...
Bianchi, Janice, Cook, Leanne, Fumarola, Sian, Ousey, Karen   +3 more
core  

A Prussian Blue Nanozyme‐Adjuvanted Vaccine Presenting Phosphocholine Antigens for Induction of Immunotolerance in Inflammatory Bowel Disease

Advanced Science, EarlyView.
This study developed a novel nano‐vaccine (Ferritin‐PC@PBNZs) comprising a ferritin‐based scaffold for the multivalent display of phosphorylcholine (PC) antigens, integrated with Prussian blue nanozymes (PBNZs) as a potent adjuvant. By leveraging the ferritin carrier for high‐density and ordered antigen display, the nano‐vaccine significantly augments ...
Jingyi Sheng, Yubo Huang, Xinyue Li, Yin Liu, Yuehuang Wu, Yuxin Zhang, Ning Gu   +6 more
wiley   +1 more source

DRD2 Dopamine Receptor and IL-1β Gene Expression Changes Involved in Wound Healing in Type 2 Diabetic Patients with Foot Ulcer

Journal of Mazandaran University of Medical Sciences, 2018
Background and purpose: Diabetic foot ulcer is a complication of type 2 diabetes. Various factors, such as changes in the level of cytokines (especially IL-1β) can interfere with the development of diabetic foot ulcer. Several factors affect the level of
Neda Ebrahimzadeh, Hajar Vaseghi, Garshasb Rigi, Gholamreza Esmaeeli Djavid, Shahla Mohammad Ganji, Amirreza Farhoud, Majid Pornour   +6 more
doaj  

A “Hot Spring” Mimetic Aerogel Loaded with Multiple Amino Acids Modulates the Chronic Inflammatory Microenvironment Through Metabolic Reprogramming

Advanced Science, EarlyView.
The SrCuSi4O₁₀ bioceramic particles mimic the effects of hot spring therapy by increasing the local wound temperature, which enhances the absorption of amino acids and stimulates cell metabolism. The amino acid uptake supports cellular glutathione redox reactions, helping to mitigate oxidative stress.
Bo Li, Dandan Jin, Fei Li, Jianliang Shen, Jiang Chang, Chen Yang, Shixuan Chen, Yi Zhang   +7 more
wiley   +1 more source

Explication of the Construct of Shared Care and the Prevention of Pressure Ulcers in Home Health Care [PDF]

, 1996
The purpose of this investigation was to render a more complete understanding of subjective perceptions of pressure ulcers from the perspective of family dyads, and to study the effect of these subjective experiences on preventive behaviors and pressure ...
Sebern, Margaret
core   +1 more source