Results 61 to 70 of about 41,923 (267)

Efficacy of Cellular Therapy for Diabetic Foot Ulcer

Cell Transplantation, 2017
Diabetes mellitus is a widely spread chronic disease with growing incidence worldwide, and diabetic foot ulcer is one of the most serious complications of diabetes.
Ye Zhang, Hong Deng, Zhouping Tang
doaj   +1 more source

A Hydrogen Sulfide–Releasing Dynamic Hydrogel Modulates Coordinated Neurovascular, Immune, and Angiogenic Responses for Scar‐Suppressed Diabetic Wound Repair

Advanced Science, EarlyView.
ROS‐Responsive H2S Hydrogel (HAPPF) Coordinated Regeneration for High‐Quality Diabetic Wound Repair.A self‐regulating dynamic hydrogel is developed to deliver a fluorogenic H2S donor in response to excessive ROS. Released H2S acts as a master regulator to resolve chronic inflammation (M2 polarization), restore VEGF‐driven angiogenesis, and rebalance ...
Xuyang Ning, Ziqiang Zhou, Bangming Li, Hong Lu, Haoyang Wen, Zhoulong Huang, Gang Li, Ping Hu   +7 more
wiley   +1 more source

Vehicle ergonomics contributing to a diabetic foot ulcer

Clinical Diabetes and Endocrinology, 2019
Background Diabetes mellitus continues to be a rising concern in the United States. It affects an estimated 9.4% of the population and approximately 1.5 million Americans are diagnosed annually.
Christine Jarocki, Brian M. Schmidt, Crystal Murray Holmes   +2 more
doaj   +1 more source

Frequency of Chronic Kidney Disease in Type 2 Diabetic Patients Presenting with Diabetic Foot Ulcer

Pakistan Journal of Medicine and Dentistry, 2020
Background: Recent evidence states that about a quarter of all diabetic patients will experience an ulcer on foot at some point in their lifetime and 15-25% of these will require foot amputation.
Sarwat Ashraf, Asif Aziz, Mir Tahir Hussain Talpur, Sagheer Ahmed Solangi, Khalil Ullah Shabir, Ghazala Usman, Moiz Ahmed, Kiran Abbas   +7 more
doaj   +1 more source

Targeting p21‐High Senescent Kupffer Cells Nanotherapeutically Potentiates Antitumor Immunity in Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombus

Advanced Science, EarlyView.
Schematic illustration of a biomimetic SKEV@AAV platform targeting p21‐high senescent Kupffer cells (sKCs) in hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT). p21‐high sKCs accumulate in the PVTT microenvironment and establish an immunosuppressive, SASP‐rich environment that facilitates tumor cell proliferation and immune evasion.
Na Ta, Shuyi Wang, Boyan Zhang, Ning Liu, Yingchen Han, Aoran Liu, Ying Xu, Tingsong Chen, Ye Zhang, Qiuhua Luo, Tao Han   +10 more
wiley   +1 more source

Biomimetic Nanoplatform for Dual Target Nano‐Metabolic Therapy in Diabetes‐Associated Biofilm Infections

Advanced Science, EarlyView.
A biomimetic GOx/Arg‐loaded nanoplatform produces nitric oxide through an in situ catalytic cascade reaction, enabling dual‐target metabolic regulation in diabetes‐associated biofilm infections. Bacterial metabolism is disrupted, and macrophage immunometabolism is reprogrammed, resulting in biofilm eradication, immune restoration, and enhanced ...
Mingzhang Li, Yonglong Li, Jiren Yan, Changming Wang, Jinlong Yu, Feng Jiang, Boyong Wang, Yi Yang, Deyi Ding, Jin Tang, Pei Han, Botao Song, Geyong Guo, Hao Shen   +13 more
wiley   +1 more source

The Evaluation of Effective Risk Factors for Foot skin in Diabetic Patients

Journal of Holistic Nursing and Midwifery, 2015
Introduction: Foot ulceration is one of the most serious and disabling complications of Diabetes Mellitus and identification of risk factors affecting foot ulcer can prevent it from causing irreparable consequences.
Pegah Piran, Farahnaz Joukar, Saghi Mousavi, Zahra, Seyed Mojtaba Mehrdad   +4 more
doaj  

Normalization of Microbiome after Diabetic Foot Ulcer Treatment

Foot & Ankle Orthopaedics, 2019
Category: Diabetes Introduction/Purpose: Diabetic ulcers carry with it extensive morbidity. The microbiome of diabetic foot infections have previously been shown to be polymicrobial.
Sebastien Stephens MD, PhD, Alexandre Stephens, Simon Platt MB ChB, FRCS   +2 more
doaj   +1 more source

Oral Prebiotic Polysaccharide Hydrogels Sustaining Colon Antibody Release Alleviate Inflammatory Bowel Disease

Advanced Science, EarlyView.
An orally administered prebiotic polysaccharide hydrogel (predaGel) based on inulin and alginate‐dopamine is stable in the stomach, adheres to the intestine, and degrades slowly in the colon. It enables site‐specific delivery of anti‐TNF‐α and anti‐IL‐12/23 antibodies, scavenges reactive oxygen species, and remodels gut microbiota, offering effective ...
Xinyi Dong, Huan He, Li Cao, Fenghua Meng, Zhiyuan Zhong   +4 more
wiley   +1 more source

Association of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 levels with diabetic foot ulcer in Egyptians with type 2 diabetes mellitus

Journal of Medicine in Scientific Research, 2018
Background The imbalance between matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1) may play an important role in impaired healing of diabetic foot ulcer.
Ghada H Sayed, Ghada A Omar, Ayat I Ghanem, Naglaa F Mohamed, Mourad I El-Kholy   +4 more
doaj   +1 more source