Results 81 to 90 of about 81,944 (308)

Diabetes Foot Ulcer Risk - A Public Health Concern in Rural Pondicherry!!

National Journal of Community Medicine, 2018
Background: The risk of diabetes related complications is increas- ing with the increase in number of diabetes in rural population. Diabetes foot ulcer is a preventable complication of diabetes. Objective: To assess the diabetes foot ulcer risk among
Bijaya N Naik, Manikandan Srinivasan, Mahendra M Reddy, Srikanta Kanungo, Sonali Sarkar, Sitanshu S Kar   +5 more
doaj  

Implications of antimicrobial combinations in complex wound biofilms containing fungi [PDF]

, 2017
Diabetic foot ulcer treatment currently focuses on targeting bacterial biofilms, while dismissing fungi. To investigate this we used an in vitro biofilm model containing bacteria and fungi, reflective of the wound environment, to test the impact of ...
Alvarez, Brem, Chellan, Chellan, Craig Williams, Donald Hansom, Dubský, Edmonds, Eleanor M. Townsend, Gordon Ramage, James, John Butcher, Kalan, Kean, Kong, Leighann Sherry, Miles, National Institute for Health and Care Excellence, Neut, Ramage, Ryan Kean, Sanchez, Sanchez, Sherry, Sherry, Smith, Townsend, William G. Mackay   +27 more
core   +4 more sources

Promotion of DFU Wound Healing via BRG1–COL16A1 Axis in Fibroblasts

Advanced Science, EarlyView.
In normal wound healing, transcription factor BRG1 is upregulated and binds the COL16A1 promoter to enhance its expression, promoting fibroblast proliferation, migration, contraction, extracellular matrix deposition, and granulation tissue formation, thus accelerating wound closure.
Penghui Wang, Jiaming Sun, Ying Wang, Bichen Ren, Yuxin Liu, Yunhan Liu, Liang Chen, Lu Yu, Tao Dai, Li Yu, Zhihui Dong   +10 more
wiley   +1 more source

A Simple New Classification for Diabetic Foot Ulcers

Medicine Science, 2015
Gangrene, infections like abscesses and ulcers are some of the common diabetic foot complications. Of all these, diabetic foot ulcers pose a major public health problem. Around 80% of all the lower limb amputations are preceded by a foot ulcer. There are
Amit Kumar C Jain
doaj   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

Pixel classification for automated diabetic foot diagnosis [PDF]

, 2009
Worldwide, more than 180 million people suffer from diabetes mellitus. Approximately 50% of these patients will develop complications to their feet. Neuropathy, combined with poor blood supply and biomechanical changes results in a high risk for foot ...
Baal, J.G. van, Bus, S.A., Hazenberg, S., Heijden, F. van der, Klein, A., Kloeze, C.   +5 more
core   +1 more source

Mitochondrial CircRNA CircMT‐RNR2 Safeguards Antioxidant Defense to Support Fibroblast Functions in Wound Repair

Advanced Science, EarlyView.
CircMT‐RNR2 promotes wound healing by enhancing fibroblast proliferation, migration, contraction, and extracellular matrix (ECM) production. It sustains mitochondrial redox balance by stabilizing the antioxidant protein PRDX3, thereby reducing ROS‐induced damage. In diabetic foot ulcers, hypoxia, hyperglycemia, and reduced FGF2 and EGF expression lower
Guanglin Niu, Jennifer Geara, Yongjian Chen, Lihua Luo, Yanwei Xiao, Zhuang Liu, Margaux Gaborieau, Ling Pan, Edmund Loh, Dongqing Li, Pehr Sommar, Aoxue Wang, Xiaowei Zheng, Ning Xu Landén   +13 more
wiley   +1 more source

Efficiency of surgical treatment of patients with diabetic foot syndrome in Nigeria [PDF]

, 2017
Diabetic foot is a foot that exhibits any pathology that results directly from diabetes mellitus or any long term (chronic) complication of diabetes mellitus.
Siki, O.P.
core  

Periodontitis Induces B Cell‐Macrophage Crosstalk to Exacerbate Glucose Dysregulation in Obesity

Advanced Science, EarlyView.
In obesity, periodontitis exacerbates hyperglycemia and exhibits a liver‐centric preference for glucose regulation. This occurs through a periodontitis‐driven circuit between pathogenic B cells and hepatic macrophages. Their reciprocal expansion, orchestrated by the NLRP3/IL‐18 signaling pathway, amplifies metabolic inflammation and disrupts glucose ...
Wen‐Zhen Lin, Lu‐Jun Zhou, Hui‐Lin Ye, Ting Liu, Bo‐Yan Chen, Xue‐Bing Bai, Jun Zhang, Lan Bai, Lin‐Juan Du, Yuan Liu, Yong‐Li Wang, Hong Zhu, Yu‐Lin Li, Shuo Xu, Xiao‐Qian Meng, Guo‐Cai Tian, Yan Liu, Wu‐Chang Zhang, Ya‐Qin Zhu, Sheng‐Zhong Duan   +19 more
wiley   +1 more source

The Evaluation of Effective Risk Factors for Foot skin in Diabetic Patients

Journal of Holistic Nursing and Midwifery, 2015
Introduction: Foot ulceration is one of the most serious and disabling complications of Diabetes Mellitus and identification of risk factors affecting foot ulcer can prevent it from causing irreparable consequences.
Pegah Piran, Farahnaz Joukar, Saghi Mousavi, Zahra, Seyed Mojtaba Mehrdad   +4 more
doaj