Results 11 to 20 of about 2,546 (143)

Foramen Magnum Stenosis in Achondroplasia: Imaging-Based Surgical Indications, Synchondrosis Fusion, and the Role of Ventriculomegaly.

Pediatr Neurosurg
Introduction: Foramen magnum stenosis (FMS) and ventriculomegaly are frequent in achondroplasia due to cranial base hypoplasia. While FMS can cause spinal cord compression, the optimal treatment strategy remains debated. We reviewed our single-center experience and explored factors influencing surgical decisions. Methods: We retrospectively analyzed 18
Ando R, Numata O.
europepmc   +2 more sources

Foramen Magnum Stenosis in Achondroplasia [PDF]

Austin Journal of Radiology, 2021
Achondroplasia is the most common hereditary skeletal dysplasia and is characterized by disproportionately short stature with rhizomelic short extremities [1]. The skull features include a narrowed foramen magnum, short skull base, and clivus [2]. Foramen magnum stenosis is a characteristic funding, secondary to an abnormal placement and premature ...
Choayb S, Adil H, El Haddad S
openaire   +1 more source

Incidence and Skeletal Features of Developmental Cervical and Lumbar Spinal Stenosis [PDF]

Asian Spine Journal, 2023
Study Design Cross-sectional study. Purpose To report the prevalence and relationship of developmental cervical and lumbar spinal stenosis (DCSS and DLSS) with the bone parameters of the skull and extremities.
Yuichi Kasai, Permsak Paholpak, Taweechok Wisanuyotin, Nattharada Sukitthanakornkul, Parika Hanarwut, Arada Chaiyamoon, Sitthichai Iamsaard, Tetsutaro Mizuno   +7 more
doaj   +1 more source

Rationale, design, and methods of a randomized, controlled, open-label clinical trial with open-label extension to investigate the safety of vosoritide in infants, and young children with achondroplasia at risk of requiring cervicomedullary decompression surgery

Science Progress, 2021
Achondroplasia causes narrowing of the foramen magnum and the spinal canal leading to increased mortality due to cervicomedullary compression in infants and significant morbidity due to spinal stenosis later in adulthood.
Ravi Savarirayan, Melita Irving, Wirginia Maixner, Dominic Thompson, Amaka C Offiah, Daniel JA Connolly, Ashok Raghavan, James Powell, Marcin Kronhardt, George Jeha, Sajda Ghani, Elena Fisheleva, Jonathan RS Day   +12 more
doaj   +1 more source

Arnold Chiari Malformation with Spina Bifida: A Lost Opportunity of Folic Acid Supplementation [PDF]

Journal of Clinical and Diagnostic Research, 2014
In Arnold Chiari (kee-AHR-ee) II malformation elongated cerebellar tonsils are displaced inferiorly through the Foramen Magnum into the upper cervical spinal canal.
Deepa Ganesh, Benjamin M Sagayaraj, Ravi Kumar Barua, Nidhi Sharma, Upasana Ranga   +4 more
doaj   +1 more source

The role of ONSD in the assessment of headache associated with Chiari malformation type 1

Frontiers in Neurology, 2023
BackgroundCough associated headache is the most common symptom in Chiari malformation type 1 (CM1). However, its pathophysiology and treatment are not clear.
Mehmet Kürşat Karadag, Mehmet Emin Akyuz, Mehmet Hakan Sahin   +2 more
doaj   +1 more source

Hypochondroplasia With Foramen Magnum Stenosis : A Case Report

Medical Journal of Trakya University, 2009
Hypochondroplasia was first reported in the English literature by Beals (1969). The features are similar to those of achondroplasia but are less severe and are usually reported not to involve the skull. The foramen magnum and whole spinal canal are reduced in diameter in achondroplasia, but less so in hypochondroplasia.
Asilioglu, Nazik, Ates, Alper, Kilinc, Ayse Ayzit, Dagcinar, Adnan   +3 more
openaire   +4 more sources

Comparative skull analysis suggests species-specific captivity-related malformation in lions (Panthera leo). [PDF]

PLoS ONE, 2014
Lion (Panthera leo) populations have dramatically decreased worldwide with a surviving population estimated at 32,000 across the African savannah.
Joseph Saragusty, Anat Shavit-Meyrav, Nobuyuki Yamaguchi, Rona Nadler, Tali Bdolah-Abram, Laura Gibeon, Thomas B Hildebrandt, Merav H Shamir   +7 more
doaj   +1 more source

Achondroplasia in Latin America: practical recommendations for the multidisciplinary care of pediatric patients

BMC Pediatrics, 2022
Background Achondroplasia is the most common bone dysplasia associated with disproportionate short stature, and other comorbidities, such as foramen magnum stenosis, thoracolumbar kyphosis, lumbar hyperlordosis, genu varum and spinal compression ...
Juan Llerena, Chong Ae Kim, Virginia Fano, Pablo Rosselli, Paulo Ferrez Collett-Solberg, Paula Frassinetti Vasconcelos de Medeiros, Mariana del Pino, Débora Bertola, Charles Marques Lourenço, Denise Pontes Cavalcanti, Têmis Maria Félix, Antonio Rosa-Bellas, Norma Teresa Rossi, Fanny Cortes, Flávia Abreu, Nicolette Cavalcanti, Maria Cecilia Hervias Ruz, Wagner Baratela   +17 more
doaj   +1 more source

Maternal administration of meclozine for the treatment of foramen magnum stenosis in transgenic mice with achondroplasia [PDF]

Journal of Neurosurgery: Pediatrics, 2017
OBJECTIVE Achondroplasia (ACH) is the most common short-limbed skeletal dysplasia caused by gain-of-function mutations in the fibroblast growth factor receptor 3 (FGFR3) gene. Foramen magnum stenosis (FMS) is one of the serious neurological complications in ACH.
Masaki, Matsushita, Kenichi, Mishima, Ryusaku, Esaki, Naoki, Ishiguro, Kinji, Ohno, Hiroshi, Kitoh   +5 more
openaire   +2 more sources