Results 111 to 120 of about 570,562 (302)

Nano-scale displacement sensing based on Van der Waals interaction

open access: yes, 2014
We propose the nano-scale displacement sensor with high resolution for weak-force systems could be realized based on vertical stacked two-dimensional (2D) atomic corrugated layer materials bound through Van der Waals (VdW) interaction.
Hu, Lin, Yang, Jinlong, Zhao, Jin
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

A Three-Axis Force Sensor for Dual Finger Haptic Interfaces

open access: yesSensors, 2012
In this work we present the design process, the characterization and testing of a novel three-axis mechanical force sensor. This sensor is optimized for use in closed-loop force control of haptic devices with three degrees of freedom.
Fabio Salsedo   +3 more
doaj   +1 more source

Displays for supervisory control of manipulators [PDF]

open access: yes
The problem of displaying information generated by sensors attached to the terminal device of a remotely controlled manipulator is considered. The sensors under consideration are proximity, force-torque, tactile and slip-page sensors. The paper describes
Bejczy, A. K., Paine, G.
core   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Compliant tactile sensor that delivers a force vector [PDF]

open access: yes, 2010
Tactile Sensor. The sensor includes a compliant convex surface disposed above a sensor array, the sensor array adapted to respond to deformation of the convex surface to generate a signal related to an applied force vector.
Torres-Jara, Eduardo
core   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Alternating current electromagnetic servo induction meter [PDF]

open access: yes, 1968
Electromagnetic device accurately indicates the responses of various sensors in high performance flight research aircraft to conditions encountered in flight.
Bogue, R. K.
core   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Validity and Reliability of Devices Measuring Countermovement Vertical Jump Performance [PDF]

open access: yes, 2019
The counter-movement jump (CMJ) test is a standard measure of lower body power and can be related to other aspects of athletic performance. With many tools commercially available, it can be difficult for professionals to distinguish which device provides
Fuller, Michael   +3 more
core   +1 more source

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