Results 131 to 140 of about 569,034 (301)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Development of Intelligent Force Sensor
Gong-kuang zidonghua, 2012 In view of problems of lower reliability in traditional differential pressure density meter and being not suitable for situation of frequent change of media density in pressure-type liquid level meter, an intelligent force sensor based on Freescale ...
CHEN Zhang-bao, LIU Ping-kuan
doaj
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Validity and Reliability of Devices Measuring Countermovement Vertical Jump Performance [PDF]
, 2019 The counter-movement jump (CMJ) test is a standard measure of lower body power and can be related to other aspects of athletic performance. With many tools commercially available, it can be difficult for professionals to distinguish which device provides
Fuller, Michael +3 more
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Journal of the Robotics Society of Japan, 1991 Kojiro OGATA, Kunio KASHIWAGI, Kozo ONO
openaire +2 more sources
FEBS Open Bio, EarlyView.This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source
Fiber Optic Sensor of Axial Strain and Dynamic Transverse Force Based on Intensity Demodulation
SensorsThis paper presents a fiber-optic sensor with intensity demodulation for simultaneous measurement of dynamic transverse force and axial strain. The sensor uses a Sagnac loop filter with a polarization-maintaining photonic crystal fiber (PM-PCF) that is ...
Cezary Kaczmarek, Malgorzata Detka
doaj +1 more source
Flight telerobot mechanism design: Problems and challenges [PDF]
Problems and challenges of designing flight telerobot mechanisms are discussed. Specific experiences are drawn from the following system developments: (1) the Force Reflecting Hand Controller, (2) the Smart End Effector, (3) the force-torque sensor, and ...
Dahlgren, John B., Kan, Edwin P.
core +1 more source