Results 91 to 100 of about 948,710 (274)

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Forced displacement in communities and districts.

, 2022
Forced displacement in communities and districts.
Tilman Brück (5195570), Moritz Hennicke (12378429)   +1 more
core   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Internal forced displacement and transformations of indigenous territorialities in Chiapas, Mexico [PDF]

ISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences
A geographical study was realized, incorporating temporal and spatial elements of the border region, on forced internal displacement (FID) in Chiapas, Mexico.
A. A. Navarro López
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Bridging Borders: The Intersection of Forced Displacement, Economic Integration, and Tourism

This chapter examines the causes and intersection of forced displacement, economic integration, tourism and hospitality, contributing to the migration-sustainable development debate in the European framework.
Morady, F.
core   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Changes in mental disorder prevalence among conflict-affected populations: a prospective study in Sri Lanka (COMRAID-R). [PDF]

, 2015
BACKGROUND: Longitudinal data are lacking on mental health trajectories following conflict resolution and return migration. COMRAID-R is a follow-up study of Muslims displaced by conflict from Northern Sri Lanka 20 years ago who are now beginning to ...
Robert Stewart, Sumathipala, Athula, Gayani Pannala, Roberts, B, Siribaddana, S, Melanie Abas, Sumathipala, A, Sisira Siribaddana, Bayard Roberts, Athula Sumathipala, Anushka Adikari, Pannala, Gayani, Siriwardhana, Chesmal, Abas, Melanie; id_orcid, Stewart, Robert, Roberts, Bayard, Adikari, A, Siribaddana, Sisira, Siriwardhana, C, Adikari, Anushka, Pannala, G, Abas, Melanie, Abas, M, Stewart, R, Chesmal Siriwardhana   +24 more
core   +2 more sources

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Electing Displacement: Political Cleansing in Apartadó, Colombia [PDF]

This article highlights a nefarious effect of elections during civil wars by demonstratingthat they can facilitate the displacement of civilians. This occurs through two main mechanisms: they reveal information about civilians' loyalties directly to ...
Abbey Steele
core