Results 81 to 90 of about 948,710 (274)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Alcohol disorder amongst forcibly displaced persons in northern Uganda. [PDF]

open access: yes, 2011
BACKGROUND: Alcohol use may be a coping mechanism for the stressors related to forced displacement. The aim of this study was to investigate levels and determinants of alcohol disorder amongst internally displaced persons (IDPs) in northern Uganda ...
Felix Ocaka, Kaducu   +9 more
core   +1 more source

Uma análise aos fluxos migratórios e dinâmicas do deslocamento forçado na Colômbia para o período 2000-2007

open access: yesConfins, 2017
One of the main consequences generated by the armed conflict in Colombia is the internal displacement. Analyze the social impacts of a conflict that has persisted for over fifty years is especially relevant because it directly affects the civilian ...
Karo Ramírez Duque
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Analysis of Vibrational Performance of A Piezoelectric Micropump with Diffuse/Nozzle Microchannel

open access: yesNanotechnology and Precision Engineering, 2018
: Piezoelectric transducers of different external diameters are designed and fabricated and incorporated into micropumps. Through finite element analysis, it is shown that the volume efficiency of the micropump reaches its maximum value for the first ...
Yanfang Guan, Xiang Li
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Displacement in communication [PDF]

open access: yes, 2012
Displacement, the ability to refer to things that are spatially and temporally remote, is one of the important features of human language. In order to clarify what is truly unique to human language, we consider displacement in the context of ...
TAKASHI HASHIMOTO   +3 more
core   +1 more source

Artificial Intelligence in migrant health: a critical perspective on opportunities and risks

open access: yesThe Lancet Regional Health. Europe
Summary: Rapid advances in Artificial Intelligence (AI) are leading to the proliferation of health applications. AI presents both opportunities and risks for migrants, including refugees, and asylum-seekers.
Stephen A. Matlin   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy