Results 21 to 30 of about 37,978 (258)

The value of migration corridors in studying health of displaced persons in West Africa

Discover Public Health
West Africa and the Sahel are in the midst of what the UNHCR terms a “crisis of displacement” as millions of people are being compelled to leave their homes due to conflict and environmental threats.
Aislinn L. Mershon, Muhammad H. Zaman
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Climate change interventions at the “top of the world”: exploring risk–risk tradeoffs in Arctic coastal protection and forest carbon removal in Alaska

Frontiers in Political Science
Alaska, the largest geographic state in the United States, experiences climate change and global warming two to three times that of the global average, leading to thawing permafrost, wildfires, and more severe storms.
Benjamin Sovacool
doaj   +1 more source

Climate Change Migration and Displacement: Learning from Past Relocations in the Pacific

Social Sciences, 2019
It has been projected that the single greatest impact of environmental changes will be on human migration and displacement. Migration has been extensively discussed and documented as an adaptation strategy in response to environmental changes, and more ...
Tammy Tabe
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Farmwork and family: How mixed-status families influence the mental health of foreign born farmworkers

SSM - Mental Health
Immigrant agricultural workers, especially unauthorized workers, face a range of severe stressors, including isolation, chronic job insecurity, and marginalization, leading to higher rates of mental health issues compared to native-born populations. This
Helen Elizabeth Lindsay, Joaquin Alfredo-Angel Rubalcaba, Samuel Ian Lidsky   +2 more
doaj   +1 more source

Introduction Environmentally Induced Displacement and Forced Migration

Refuge, 2014
Disappearing coastlines, fields and homes flooded by rising waters, lands left cracked and barren by desertification, a snowpack shrinking in circumpolar regions year by year—these are only a few of the iconic images of climate change that have evoked ...
Pablo Bose, Elizabeth Lunstrum
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Microplastics as active modulators of Escherichia coli biofilm characteristics and their implications on the development of antimicrobial resistance

Biofilm
Microplastics are increasingly recognized as substrates that facilitate microbial colonization and may contribute to antimicrobial resistance, yet their role in shaping biofilm physiology remains poorly understood.
Yanina Nahum, Neila Gross, Johnathan Muhvich, Muhammad H. Zaman   +3 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source