Results 41 to 50 of about 37,978 (258)
Microplastics (MPs) have emerged as a significant environmental pollutant with profound implications for public health, particularly as substrates to facilitate bacterial antimicrobial resistance (AMR).
Neila Gross +6 more
doaj +1 more source
Protect Civilians from the Crime of Forced Displacement Under Ihl An Analytical Study / حماية المدنيين من جريمة التهجير القسري بموجب القانون الدولي الإنساني " دراسة تحليلية " [PDF]
The study seeks to clarify the concept of forced displacement, its effects, and shed light on international protection mechanisms for civilians from forced displacement under international humanitarian law, and the extent of the adequacy of ...
إعتصام العبد صالح الوهيبي
doaj +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Forced Displacement and Refugees [PDF]
Forced migration has come to be the defining feature of the contemporary Middle East, a region that is both the source of and host to some of the largest forcibly displaced populations in the world. In 2015, 65 percent of the world's 19.4 million refugees—including the 5.5 million Palestinian refugees—as well as 30 percent of the world's thirty-eight ...
openaire +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Towards a development approach to displacement
To better respond to displacement, we need to adopt a medium- to long-term perspective rooted in development as well as humanitarian principles.
Xavier Devictor
doaj
[Displaced women's opinion of the impact of forced displacement on their health].
To analyze the adaptation process of women internally displaced to the city and the relationship between displacement and their self-perceived main health problems.A qualitative, exploratory, descriptive study was carried out by means of semi-structured individual interviews with a maximum variation sample of 25 internally displaced women.
Mogollón Pérez, Amparo Susana +1 more
openaire +2 more sources
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source

