Results 31 to 40 of about 37,978 (258)

Infectious disease research in forcibly displaced populations: A systematic review in low- and middle-income host countries

Journal of Migration and Health
Background: Infectious disease research is essential for disease prevention and management within refugee camps and informal settlements. The objective of this study is to identify the characteristics of existing infectious disease research in these ...
Neila Gross, Maia C. Tarnas, Rashmina J. Sayeeda, Carly Ching, David Flynn, Muhammad H Zaman   +5 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Refugees and host communities’ vulnerability to climate and disaster risks in Rwanda

Frontiers in Climate
Climate change hazards pose significant risks to vulnerable populations, particularly refugees residing in camps within environmentally sensitive areas. This study assesses climate and disaster risks in refugee-hosting districts in Rwanda using GIS-based
Nfamara K. Dampha, Nfamara K. Dampha, Colette Salemi, Stephen Polasky, Stephen Polasky, Amare Gebre Egziabher, Wendy Rappeport   +6 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

(Im)permanent Settlement: Protracted Displacement and Secondary Movement Experiences of Syrian Refugees from Turkey to Austria

Social Sciences
In 2022, Austria experienced a significant surge in Syrian arrivals. Unlike refugees arriving to Europe in 2015/2016, who predominantly embarked on direct journeys from Syria, most of the recently admitted cohort experienced protracted displacement in ...
Judith Kohlenberger, Sophie Reichelt, Kotayba Kadri   +2 more
doaj   +1 more source

Forced displacement of Burmese people [PDF]

Forced Migration Review, 2008
This issue of FMR aims to help bring the crisis of forceddisplacement of Burmese people back into theinternational spotlight.
Inge Brees
doaj  

Analysis of health overseas development aid for internally displaced persons in low- and middle-income countries

Journal of Migration and Health, 2022
Background: There are an estimated 55 million internally displaced persons (IDPs) globally. IDPs commonly have worse health outcomes than host populations and other forcibly displaced populations such as refugees. Official development assistance (ODA) is
Bayard Roberts, Winifred Ekezie, Kiran Jobanputra, James Smith, Sara Ellithy, David Cantor, Neha Singh, Preeti Patel   +7 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Biofilms as potential reservoirs of antimicrobial resistance in vulnerable settings

Frontiers in Public Health
Antimicrobial resistance is a major global health threat, characterized by the ability of microorganisms to withstand the effects of antimicrobial agents. Biofilms, as unique microbial communities, significantly contribute to this threat.
Yanina Nahum, Yanina Nahum, Johnathan Muhvich, José Rubén Morones-Ramirez, José Rubén Morones-Ramirez, Nestor G. Casillas-Vega, Muhammad H. Zaman, Muhammad H. Zaman   +7 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source