Results 11 to 20 of about 7,358,201 (293)
Forced Swim Reliability for Exercise Testing in Rats by a Tethered Swimming Apparatus
Frontiers in Physiology, 2018 To assess the physical capacity of rats in forced swim tests, the animal should perform a continuous activity (CON) at the surface to avoid apnea. Bobbing movement (BOB), vigorous paddling known as climbing (CLI), and diving activity (DIV) are inadequate
Ivan G. M. dos Reis +3 more
doaj +3 more sources
The effects of resveratrol on rat behaviour in the forced swim test [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2013 Introduction. The trans-isomer of resveratrol is the active ingredient of Poligonum cuspidatum, known for its medicinal properties and traditionally used in the treatment of neuropsychiatric disorders.
Samardžić Janko +6 more
doaj +3 more sources
Forced swim test in mice: A common animal model of depression [PDF]
Bangladesh Journal of Pharmacology, 2015 The Forced Swim Test (FST) is a rodent behavioral paradigm utilized for assessment of potential antidepressant-like medications. In this model the mice are put in a plexiglas tank.
Muhammad Aslam
doaj +1 more source
The mouse forced swim test. [PDF]
J Vis Exp, 2012 The forced swim test is a rodent behavioral test used for evaluation of antidepressant drugs, antidepressant efficacy of new compounds, and experimental manipulations that are aimed at rendering or preventing depressive-like states. Mice are placed in an inescapable transparent tank that is filled with water and their escape related mobility behavior ...
Can A +5 more
europepmc +4 more sources
Forced swim test: What about females?
Neuropharmacology, 2015 In preclinical studies screening for novel antidepressants, male and female animals should be used. However, in a widely used antidepressant test, the forced swim test (FST), sex differences between males and females are not consistent. These discrepancies may discourage the inclusion of females in FST studies.
Nikolaos Kokras +5 more
openaire +4 more sources
Time to abolish the forced swim test in depression research? [PDF]
, 2021 Funding: This publication was financed by Portuguese national funds within the CFCUL – Centro de Filosofia das Ciência da Universidade de Lisboa, research center strategic project, ref.
Marques, Tiago A. +10 more
core +1 more source
Antidepressant Effect of Ketamine in Sub Anaesthetic Doses in Male Albino Mice [PDF]
Journal of Clinical and Diagnostic Research, 2014 Background: Depression is the most common mental disorder in community settings, and is a major cause of disability across the world. Antidepressants such as SSRI (Selective Serotonin Reuptake Inhibitor) and TCA (Tricyclic antidepressants) are used ...
Lourdu Jafrin Antony +2 more
doaj +1 more source
X-Irradiation at 0.5 Gy after the forced swim test reduces forced swimming-induced immobility in mice. [PDF]
J Radiat Res, 2020 Abstract The forced swim test (FST) is a screening model for antidepressant activity; it causes immobility and induces oxidative stress. We previously reported that radon inhalation has antidepressant-like effects in mice potentially through the activation of antioxidative functions upon radon inhalation.
Kataoka T +9 more
europepmc +5 more sources
Effect of Ocimum tenuiflorum extract on immobility time of rats subjected to forced swim test.
, 2023 Ocimum tenuiflorum extract at 6.5, 12.5, and 25 mg/kg doses were evaluated in the forced swim test. The immobility time of animals during a 5-minute forced swim test was noted for each animal.
Bharathi Bethapudi (12057731) +5 more
core +1 more source
Kpna1 KO mice show increased depression-like behavior in the forced swim test.
, 2021 Assessment of depression-like behaviors in the forced swim test (FS) in group-housed and isolated WT and Kpna1 KO mice. Time spent immobile (s) in the FS. Mean ± SEM, * p Kpna1 KO; isolated: 10 WT, 9 Kpna1 KO.
Taichi Itou (11690204) +11 more
core +1 more source