Results 21 to 30 of about 7,358,201 (293)
Forced swim test behavior in postpartum rats [PDF]
Pharmacology Biochemistry and Behavior, 2010 This study was undertaken to determine whether depression-like behavior can be observed in gonadally intact females that have experienced normal pregnancy. When tested on the forced swim test (FST) on postpartum days 1-7, previously pregnant rats spent slightly more time immobile, significantly less time swimming and diving, and defecated more than ...
CRAFT, R. M +4 more
openaire +3 more sources
, 2023 Searchable spreadsheet with all described data within the publication "A systematic mapping review of the evolution of the rat Forced Swim Test: protocols and outcome parameters"
Cathalijn Leenaars, Christiane Brandwein
core +1 more source
11-β hydroxysteroid type 1 knockout mice display an antidepressant-like phenotype in the forced swim test [PDF]
, 2016 Objective 11-dehydroxysteroid dehydrogenase (HSD) types 1 and 2, enzymes are involved in the activation and inactivation of glucocorticoids in vivo, respectively.
Slattery, David A. +2 more
core +1 more source
Toxins, 2021 Parkinson’s patients often suffer from depression and anxiety, for which there are no optimal treatments. Hemiparkinsonian (hemi-PD) rats were used to test whether intrastriatal Botulinum neurotoxin-A (BoNT-A) application could also have antidepressant ...
Veronica Antipova +4 more
doaj +1 more source
Effect of lethal yellow (AY) mutation and photoperiod alterations on mouse behavior
Вавиловский журнал генетики и селекции, 2019 Decrease in natural illumination in fall/winter months causes depressive-like seasonal affective disorders in vulnerable individuals. Obesity is another risk factor of depression.
E. Y. Bazhenova +4 more
doaj +1 more source
GC-MS profiling and antidepressant-like effect of the extracts of Hamelia patens in animal model
Bangladesh Journal of Pharmacology, 2017 Hamelia patens is used in folk medicine in the treatment of nervous shock. The present study deals to evaluate the antidepressant-like effects of chloroform and methanol extracts of H.
Ajaykumar Rikhabchand Surana +1 more
doaj +1 more source
A study on antidepressant-like effect of dihydroxy flavones in mice and their mechanisms involved
National Journal of Physiology, Pharmacy and Pharmacology, 2018 Background: In the treatment of depression, drugs with a quick onset of action and high margin of safety are intensely being searched. Previous studies indicate flavonoids as a potential source for such drugs.
Nithya Panneerselvam +3 more
doaj +1 more source
Pharmacology Research & Perspectives, 2022 Modulation of the endocannabinoid system (ECS) is a novel putative target for therapeutic intervention in depressive disorders. Altering concentrations of one of the principal endocannabinoids, N‐arachidonoylethanolamine, also known as anandamide (AEA ...
Wahid Zada +9 more
doaj +1 more source
The forced swim test as a model of depressive-like behavior. [PDF]
J Vis Exp, 2015 The goal of the present protocol is to describe the forced swim test (FST), which is one of the most commonly used assays for the study of depressive-like behavior in rodents. The FST is based on the assumption that when placing an animal in a container filled with water, it will first make efforts to escape but eventually will exhibit immobility that ...
Yankelevitch-Yahav R +3 more
europepmc +4 more sources
Maternal deprivation enhances behavioral vulnerability to stress associated with miR-504 expression in nucleus accumbens of rats. [PDF]
PLoS ONE, 2013 OBJECTIVE: In this study, the effect of maternal deprivation (MD) and chronic unpredictable stress (CUS) in inducing depressive behaviors and associated molecular mechanism were investigated in rats.
Yi Zhang +5 more
doaj +1 more source