Results 41 to 50 of about 1,197,506 (281)

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

The Fractal Density Structure in Supersonic Isothermal Turbulence: Solenoidal versus Compressive Energy Injection

, 2009
In a systematic study, we compare the density statistics in high resolution numerical experiments of supersonic isothermal turbulence, driven by the usually adopted solenoidal (divergence-free) forcing and by compressive (curl-free) forcing. We find that
Ballesteros-Paredes, Boldyrev, Christoph Federrath, Dib, Dubey, Elmegreen, Esquivel, Falgarone, Federrath, Frisch, Fryxell, Heitsch, Hetem, Heyer, Kim, Klessen, Klessen, Kowal, Kritsuk, Kritsuk, Larson, Lee, Lemaster, Li, Mac Low, Mac Low, Mandelbrot, Mandelbrot, Offner, Ostriker, Padoan, Padoan, Padoan, Padoan, Passot, Peitgen, Perault, Ralf S. Klessen, Stone, Stutzki, Sánchez, Sánchez, Vogelaar, Vogelaar, Vázquez-Semadeni, Westpfahl, Wolfram Schmidt   +46 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Combined Optic-Acoustic Monitoring of Combustion in a Gas Turbine

International Journal of Turbomachinery, Propulsion and Power, 2020
The need for better combustion monitoring in gas turbines has become more acute with the latest technical requirements, standards, and policies in terms of safety, environment, efficiency, operation flexibility, and operation costs.
Fabrice Giuliani, Lukas Andracher, Vanessa Moosbrugger, Nina Paulitsch, Andrea Hofer   +4 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Adjustments to Climate Perturbations—Mechanisms, Implications, Observational Constraints

AGU Advances
Since the 5th Assessment Report of the Intergovernmental Panel on Climate Change (AR5) an extended concept of the energetic analysis of climate change including forcings, feedbacks and adjustment processes has become widely adopted.
Johannes Quaas, Timothy Andrews, Nicolas Bellouin, Karoline Block, Olivier Boucher, Paulo Ceppi, Guy Dagan, Sabine Doktorowski, Hannah Marie Eichholz, Piers Forster, Tom Goren, Edward Gryspeerdt, Øivind Hodnebrog, Hailing Jia, Ryan Kramer, Charlotte Lange, Amanda C. Maycock, Johannes Mülmenstädt, Gunnar Myhre, Fiona M. O’Connor, Robert Pincus, Bjørn Hallvard Samset, Fabian Senf, Keith P. Shine, Chris Smith, Camilla Weum Stjern, Toshihiko Takemura, Velle Toll, Casey J. Wall   +28 more
doaj   +1 more source

Preface: Ozone Evolution in the Past and Future

Atmosphere, 2020
The stratospheric ozone plays an important role in the protection of the biosphere from the dangerous ultraviolet radiation of the sun [...]
Eugene Rozanov
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Characterization of All Graphs with a Failed Skew Zero Forcing Number of 1

Mathematics, 2022
Given a graph G, the zero forcing number of G, Z(G), is the minimum cardinality of any set S of vertices of which repeated applications of the forcing rule results in all vertices being in S.
Aidan Johnson, Andrew E. Vick, Darren A. Narayan   +2 more
doaj   +1 more source