Results 51 to 60 of about 35,403 (305)

A Discussion on the Effective Ventilation Distance in Dead-End Tunnels

open access: yesEnergies, 2019
Forcing ventilation is the most widely used system to remove noxious gases from a working face during tunnel construction. This system creates a region near the face (dead zone), in which ventilation takes place by natural diffusion, rather than being ...
Manuel García-Díaz   +3 more
doaj   +1 more source

Virtual mode in a discipline in the Medicine career in times of pandemic: students’ perception

open access: yesRed U, 2020
COVID-19 has broken into the lives of the world’s citizens, forcing to quarantine. Higher Education was no stranger to this phenomenon. The face-to-face became virtual. Students’ vision is important in this setting.
Victor Olegario Giayetto   +3 more
doaj   +1 more source

Teleconnections link to summer heat extremes in the south-central U.S.: Insights from CMIP5 and CMIP6 simulations

open access: yesWeather and Climate Extremes, 2023
This study examines the relationship between teleconnections, which represent quasiperiodic modes of large-scale atmospheric and oceanic variability, and extreme heatwaves in the south-central (SC) U.S.
Jung-Hee Ryu, Song-Lak Kang
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Expert judgments about transient climate response to alternative future trajectories of radiative forcing

open access: yes, 2010
There is uncertainty about the response of the climate system to future trajectories of radiative forcing. To quantify this uncertainty we conducted face-to-face interviews with 14 leading climate scientists, using formal methods of expert ...
David J. Frame   +3 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Preparing for self-preservation

open access: yesForced Migration Review, 2016
All too often, violence proves to be beyond influence, forcing international aid agencies to pull back and leave local civilians to face the danger alone.
Casey Barrs
doaj  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Plant photosynthesis and productivity on Earth in the high Carbon Dioxide 21st century [PDF]

open access: yes, 2012
Understanding how plant productivity responds to CO2 is crucial to understanding Earth System dynamics and therefore, predicting the Earth System’s response to anthropogenic forcing of atmospheric CO2.
Walker, Anthony
core  

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