Results 61 to 70 of about 35,403 (305)

Infragravity wave generation on shore platforms: bound long wave versus breakpoint forcing [PDF]

open access: yes, 2020
Shore platforms are ubiquitous morphological features along rocky coastlines and display a spectrum of forms from gently-sloping to sub-horizontal with a low tide cliff.
Masselink, Gerd   +9 more
core   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Storm-wave development of shore-normal grooves (gutters) on a steep sandstone beach face [PDF]

open access: yes, 2018
Shore-normal grooves (gutters) cut into the seabed have been reported widely from the marine geological record. Grooves commonly are spaced regularly across plane, consolidated surfaces in the littoral and sub-littoral zones and may be deeply incised ...
Williams, J.   +10 more
core   +1 more source

Switching from Face-to-Face to Online Instruction Midsemester Impacts and Challenges for Student Learning and Success

open access: yes, 2021
The COVID-19 pandemic disrupted higher education during Spring 2020 by forcing all face-to-face classes to unexpectedly transition to online learning. To better understand how switching to remote learning affected students and the factors that impacted ...
Herold, Debora, Chen, Tina
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Let's Contribute to Protecting our Planet by Reducing the Brightness of Paper: Less is More

open access: yesBioResources, 2022
Sustaining life on the Earth with its ever-growing population is forcing changes in people’s way of life, industrial and agricultural production, exploitation of energy resources, and approaches to ecology.
Michal Jablonsky, Jozef Šima
doaj   +2 more sources

NUMERICAL ANALYSIS OF AIRFLOW AND METHANE EMITTED FROM THE MINE FACE IN A BLIND DOG HEADING [PDF]

open access: yesManagement Systems in Production Engineering, 2015
Ventilation is one of the most common presented problems during the driving of dog headings. During driving such heading has only one connection with air stream routes, which significantly make difficult the process of its ventilation.
Jarosław BRODNY, Magdalena TUTAK
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Supervision Practice in the Face of Emerging Health Risks: How Market Dynamics are Forcing Enforcement Officials to Stretch their Mandate

open access: yesUtrecht Law Review, 2019
The modern health care landscape is increasingly hard to capture in regulation and difficult to control by supervision agencies since, due to technological innovation and societal developments, new products and new health risks often emerge that extant ...
Aute Kasdorp, Judith van Erp
doaj   +1 more source

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