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Mitochondria in Early Forebrain Development: From Neurulation to Mid-Corticogenesis

open access: yesFrontiers in Cell and Developmental Biology, 2021
Function of the mature central nervous system (CNS) requires a substantial proportion of the body’s energy consumption. During development, the CNS anlage must maintain its structure and perform stage-specific functions as it proceeds through discrete ...
Ryann M. Fame, Maria K. Lehtinen
doaj   +1 more source

Neuromorphological Atlas of Human Prenatal Brain Development: White Paper

open access: yesLife, 2023
Recent morphological data on human brain development are quite fragmentary. However, they are highly requested for a number of medical practices, educational programs, and fundamental research in the fields of embryology, cytology and histology ...
Alexandra Proshchina   +9 more
doaj   +1 more source

Basal forebrain amnesia

open access: bronzeHigher Brain Function Research, 2011
Michitaka Funayama
openalex   +3 more sources

Association of Caspase 3 Activation and H2AX γ Phosphorylation in the Aging Brain: Studies on Untreated and Irradiated Mice

open access: yesBiomedicines, 2021
Phosphorylation of H2AX is a response to DNA damage, but γH2AX also associates with mitosis and/or apoptosis. We examined the effects of X-rays on DNA integrity to shed more light on the significance of H2AX phosphorylation and its relationship with ...
Nadia Gionchiglia   +3 more
doaj   +1 more source

Trace elements changes in the forebrain and their influence on the rats behavior in elevated plus maze in acute period of mild blast-induced traumatic brain injury

open access: yesMedičnì Perspektivi, 2023
The relevance of the study is related to the high frequency of blast-induced brain injury in both military and civilian populations, which is caused by the use of various types of explosives in military conflicts, including in Ukraine today.
Yu.V. Kozlova
doaj   +1 more source

Teleost Fish and Organoids: Alternative Windows Into the Development of Healthy and Diseased Brains

open access: yesFrontiers in Molecular Neuroscience, 2022
The variety in the display of animals’ cognition, emotions, and behaviors, typical of humans, has its roots within the anterior-most part of the brain: the forebrain, giving rise to the neocortex in mammals.
Giulia Fasano   +4 more
doaj   +1 more source

Multiple roles of Activin/Nodal, bone morphogenetic protein, fibroblast growth factor and Wnt/β-catenin signalling in the anterior neural patterning of adherent human embryonic stem cell cultures [PDF]

open access: yesOpen Biology, 2013
Several studies have successfully produced a variety of neural cell types from human embryonic stem cells (hESCs), but there has been limited systematic analysis of how different regional identities are established using well-defined differentiation ...
Giuseppe Lupo   +8 more
doaj   +1 more source

Balancing WNT signalling in early forebrain development: The role of LRP4 as a modulator of LRP6 function

open access: yesFrontiers in Cell and Developmental Biology, 2023
The specification of the forebrain relies on the precise regulation of WNT/ß-catenin signalling to support neuronal progenitor cell expansion, patterning, and morphogenesis.
Shuang Geng   +9 more
doaj   +1 more source

Forebrain pain mechanisms [PDF]

open access: yesBrain Research Reviews, 2009
Emotional-affective and cognitive dimensions of pain are less well understood than nociceptive and nocifensive components, but the forebrain is believed to play an important role. Recent evidence suggests that subcortical and cortical brain areas outside the traditional pain processing network contribute critically to emotional-affective responses and ...
NEUGEBAUER V.   +3 more
openaire   +3 more sources

Forebrain E-I balance controlled in cognition through coordinated inhibition and inhibitory transcriptome mechanism

open access: yesFrontiers in Cellular Neuroscience, 2023
IntroductionForebrain neural networks are vital for cognitive functioning, and their excitatory-inhibitory (E-I) balance is governed by neural homeostasis.
Tian Tian   +6 more
doaj   +1 more source

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