Results 201 to 210 of about 185,793 (320)

Loss of forebrain MTCH2 decreases mitochondria motility and calcium handling and impairs hippocampal-dependent cognitive functions [PDF]

open access: gold, 2017
Antonella Ruggiero   +11 more
openalex   +1 more source

Salt Stress Adaptations in Soybean Involve Alterations in Pre‐mRNA Processing

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Salt stress can seriously affect plant survival. To adapt to salt stress, plants can alter gene expressions and/or pre‐mRNA processing patterns, or both. Previous studies could not comprehensively profile stress‐responsive pre‐mRNA processing patterns due to limitations in traditional sequencing technologies.
Shoudong Zhang   +9 more
wiley   +1 more source

Association between basal forebrain volume and age in the presenilin-1 E280A autosomal dominant Alzheimer's disease kindred. [PDF]

open access: yesAlzheimers Dement
He B   +18 more
europepmc   +1 more source

Brain Dose–Volume Thresholds and Survival in Dogs With Intracranial Tumours Treated With the 10 × 4 Gy Radiotherapy Schedule: A Combined Analysis of Two Trials

open access: yesVeterinary and Comparative Oncology, EarlyView.
ABSTRACT Dogs with intracranial tumours routinely receive radiotherapy, yet species‐specific dose–volume constraints for normal brain tissue remain undefined. In human radiation oncology, exceeding certain brain dose–volume thresholds markedly increases the risk of radiation‐induced injury (e.g., radionecrosis).
Sergejs Unterkirhers   +2 more
wiley   +1 more source

Lower cerebral blood flow but not cerebrovascular response in elastin haploinsufficient mice

open access: yesExperimental Physiology, EarlyView.
Abstract Elastin insufficiency is associated with structural differences in the large elastic arteries and cerebral artery dysfunction. However, previous studies have not assessed potential sex differences in cerebrovascular function. We measured cerebral blood flow (CBF) using arterial spin labeling MRI at rest and in response to hypercapnia challenge
Abigail E. Cullen   +15 more
wiley   +1 more source

Multiomic Analyses Reveal Brainstem Metabolic Changes in a Mouse Model of Dravet Syndrome. [PDF]

open access: yesCells
Sri Hari A   +13 more
europepmc   +1 more source

Cardiac‐specific Kv1.1 deficiency alters cardiomyocyte electrophysiology without modifying overall cardiac function or arrhythmia susceptibility

open access: yesExperimental Physiology, EarlyView.
Abstract The leading cause of epilepsy‐related mortality is sudden unexpected death in epilepsy (SUDEP), resulting from seizure‐induced cardiorespiratory arrest by mechanisms that remain unresolved. Mutations in ion channel genes expressed in both brain and heart represent SUDEP risk factors because they can disrupt neural and cardiac rhythms ...
Kelsey Halvorson   +11 more
wiley   +1 more source

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