Results 151 to 160 of about 449,929 (285)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

A machine learning approach to predict river hydrographs for water quality sampling. [PDF]

Environ Monit Assess
Wilson E, Shaw M, Bennett F, Bainbridge Z, Wallace S, Turner R.   +5 more
europepmc   +1 more source

Analysts’ EPS Forecasts: The Effects of Forecast Uncertainty and Forecast Precision on Investors’ Judgments of Forecast Reliability [PDF]

SSRN Electronic Journal, 2020
openaire   +1 more source

Forecast Encompassing Tests and Probability Forecasts [PDF]

We consider tests of forecast encompassing for probability forecasts, for both quadratic and logarithmic scoring rules. We propose test statistics for the null of forecast encompassing, present the limiting distributions of the test statistics, and ...
Harvey, David I, Clements, Michael P
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Pathogen Forecast Model Version 1.0: A Process-based Five-Day Beach Advisory Forecast System for the San Diego/Tijuana Region. [PDF]

Environ Sci Technol
Feddersen F, Spydell MS, Gupta A, Giddings SN, Ruiz de Alegría Arzaburu A, Brunjes I, Olfe C, Anderson C, Barton AD, Behrens J, Berman K, Bowman J, Cornuelle BD, Gopalakrishnan G, Marhoefer-Jess S, Send U, Lankhorst M, Quiros NC.   +17 more
europepmc   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Observed and Forecasted Antibiotic Consumption by ATC/DDD Metrics: A Real-World Modeling Study with Implications for Antimicrobial Stewardship. [PDF]

Antibiotics (Basel)
Bekyarov P, Lambev M, Mihaylova S.
europepmc   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Deep forecasting architectures mirror ecological time scales in water quality prediction. [PDF]

Environ Sci Ecotechnol
Yu Y, Zhang M, Liang Z, Qu F, Wang Y, Kong X, Rinke K, Chen N.   +7 more
europepmc   +1 more source